Cancer has been a great threat to humans for decades. Due to the limitations of
monotherapy, combinational therapies such as photothermal therapy (PTT) and …

Infections in the first year of life are common and often severe. The newborn host
demonstrates both quantitative and qualitative differences to the adult in nearly all aspects of …

Global deployment of vaccines that can provide protection across several age groups is still
urgently needed to end the COVID-19 pandemic, especially in low-and middle-income …

Personalized cancer vaccines (PCVs) are reinvigorating vaccine strategies in cancer
immunotherapy. In contrast to adoptive T-cell therapy and checkpoint blockade, the PCV …

Engineering vaccine-based therapeutics for infectious diseases is highly challenging, as
trial formulations are often found to be nonspecific, ineffective, thermally or hydrolytically …

Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics
Toward precision adjuvants: optimizing science and safety : Current Opinion in Pediatrics Log …

Pregnancy comprises a unique immunological condition, to allow fetal development and to
protect the host from pathogenic infections. Viral infections during pregnancy can disrupt …

Over the last decade, C-type lectin-like receptors (CTLRs), expressed mostly by myeloid
cells, have gained increasing attention for their role in the fine tuning of both innate and …

Pathogens comprise a diverse set of immunostimulatory molecules that activate the innate
immune system during infection. The immune system recognizes distinct combinations of …

The need for new adjuvants is absolutely cardinal to the development of new vaccines and
to further optimizing current immunization approaches. However, only a few classes of …