Hypothyroidism in context: where we've been and where we're going

L Chiovato, F Magri, A Carlé - Advances in therapy, 2019 - Springer
Hypothyroidism affects up to 5% of the general population, with a further estimated 5% being
undiagnosed. Over 99% of affected patients suffer from primary hypothyroidism. Worldwide …

Subclinical hypothyroidism: a review

B Biondi, AR Cappola, DS Cooper - Jama, 2019 - jamanetwork.com
Importance Subclinical hypothyroidism, defined as an elevated serum thyrotropin (often
referred to as thyroid-stimulating hormone, or TSH) level with normal levels of free thyroxine …

Thyroid and cardiovascular disease: research agenda for enhancing knowledge, prevention, and treatment

AR Cappola, AS Desai, M Medici, LS Cooper, D Egan… - Circulation, 2019 - Am Heart Assoc
Thyroid hormones have long been known to have a range of effects on the cardiovascular
system. However, significant knowledge gaps exist concerning the precise molecular and …

A renewed focus on the association between thyroid hormones and lipid metabolism

LH Duntas, G Brenta - Frontiers in endocrinology, 2018 - frontiersin.org
Thyroid dysfunction, manifesting as either overt or subclinical hypothyroidism, negatively
affects lipid metabolism: this leads to hypercholesterolemia which progressively increases …

Management of primary hypothyroidism: statement by the British Thyroid Association Executive Committee

O Okosieme, J Gilbert, P Abraham… - Clinical …, 2016 - Wiley Online Library
The management of primary hypothyroidism with levothyroxine (L‐T4) is simple, effective
and safe, and most patients report improved well‐being on initiation of treatment. However …

Thyroid allostasis–adaptive responses of thyrotropic feedback control to conditions of strain, stress, and developmental programming

A Chatzitomaris, R Hoermann, JE Midgley… - Frontiers in …, 2017 - frontiersin.org
The hypothalamus–pituitary–thyroid feedback control is a dynamic, adaptive system. In
situations of illness and deprivation of energy representing type 1 allostasis, the stress …

Thyroid hormone therapy for hypothyroidism

B Biondi, DS Cooper - Endocrine, 2019 - Springer
The purpose of this article will be to review the basics of thyroid hormone therapy, including
various thyroid hormone formulations, the institution and monitoring of thyroid hormone …

[HTML][HTML] Impactos das práticas integrativas e complementares na saúde de pacientes crônicos

MPO Dacal, IS Silva - Saúde em debate, 2018 - SciELO Public Health
RESUMO A inclusão das práticas integrativas e complementares nos serviços de saúde
pública tem acontecido de forma gradual e lentificada, há cerca de 10 anos. Este estudo …

Subclinical hypothyroidism in older individuals

B Biondi, AR Cappola - The Lancet Diabetes & Endocrinology, 2022 - thelancet.com
Subclinical hypothyroidism, which is defined as a thyroid-stimulating hormone concentration
higher than the reference range (generally 4· 5 mIU/L or higher) with normal free thyroxine …

Levothyroxine for the treatment of subclinical hypothyroidism and cardiovascular disease

LY Sue, AM Leung - Frontiers in endocrinology, 2020 - frontiersin.org
Subclinical hypothyroidism is a biochemical condition defined by elevated serum thyroid-
stimulating hormone levels in the setting of normal levels of the peripheral thyroid hormones …