Memory T cells form an essential part of immunological memory, which can last for years or
even a lifetime. Much experimental work has shown that the individual cells that make up the …

Age‐related changes in human T‐cell populations are important contributors to
immunosenescence. In particular, terminally differentiated CD8+ effector memory CD45RA+ …

Infectious diseases such as SARS-CoV-2 pose a considerable threat to public health.
Constructing a reliable mathematical model helps us quantitatively explain the kinetic …

High-dimensional flow cytometry is the gold standard to study the human immune system in
large cohorts. However, large sample sizes increase inter-experimental variation because of …

Cytomegalovirus (CMV), a DNA virus that belongs to the Orthoherpesviridae family, infects
40–100% of people. Primary/non-primary CMV infection during pregnancy could cause fetal …

Meta-analyses confirm a link between persistent human cytomegalovirus (HCMV) infections
and cardiovascular disease, but the mechanisms are unclear. We assess whether …

Introduction Accumulating evidence indicates the importance of T cell immunity in
vaccination-induced protection against severe COVID-19 disease, especially against SARS …

Accurate prediction of the temporal and spatial characteristics of COVID-19 infection is of
paramount importance for effective epidemic prevention and control. In order to accomplish …

Persistent infections with human cytomegalovirus (HCMV) affect the hosts' immune system
and have been linked with chronic inflammation and cardiovascular disease. These effects …

The potential of memory T cells to provide protection against reinfection is beyond question.
Yet, it remains debated whether long-term T cell memory is due to long-lived memory cells …