Cahn–Hilliard models for glial cells

L Li, A Miranville, R Guillevin - Applied Mathematics & Optimization, 2021 - Springer
Our aim in this paper is to study a Cahn–Hilliard model with a symport term. This equation is
proposed to model some energy mechanisms (eg, lactate) in glial cells. The main difficulty is …

On a tumor growth model with brain lactate kinetics

L Cherfils, S Gatti, C Guillevin… - … and Biology: A …, 2022 - academic.oup.com
Our aim in this paper is to study a mathematical model for high grade gliomas, taking into
account lactates kinetics, as well as chemotherapy and antiangiogenic treatment. In …

Mathematical analysis of a phase-field model of brain cancers with chemotherapy and antiangiogenic therapy effects

M Conti, S Gatti, A Miranville - AIMS MATHEMATICS, 2022 - iris.unimore.it
Our aim in this paper is to study a mathematical model for brain cancers with chemotherapy
and antiangiogenic therapy effects. We prove the existence and uniqueness of biologically …

Mathematical analysis of a model for proliferative-to-invasive transition of hypoxic glioma cells

M Conti, S Gatti, A Miranville - Nonlinear Analysis, 2019 - Elsevier
Our aim in this paper is to study a mathematical model for the proliferative-to-invasive
transition of hypoxic glioma cells. We prove the existence and uniqueness of nonnegative …

Numerical analysis of a mathematical model describing the evolution of hypoxic glioma cells

JL López-Agredo, DA Rueda-Gómez… - … & Mathematics with …, 2023 - Elsevier
In this work, we develop the numerical analysis of a parabolic system of PDE describing the
proliferation-invasion structure of hypoxic glial cells in the brain. Explicitly, we propose a fully …

Optimal control of therapies on a tumor growth model with brain lactate kinetics

L Cherfils, S Gatti, A Miranville, H Raad… - … Dynamical Systems-S, 2024 - aimsciences.org
We prove the existence of an optimal treatment combining chemotherapy and a lactate
targeting drug for a mathematical model for high grade gliomas and lactate kinetics. A …

Theoretical and numerical analysis of a parabolic system with chemoattraction modeling the growth of glioma cells

JL López-Agredo, DA Rueda-Gómez… - Applied Numerical …, 2023 - Elsevier
In this paper, we consider a two dimensional PDE model describing the proliferation-
invasion structure of hypoxic glial cells in the brain, in which the cell movement is …

How heterogeneity drives tumour growth: a computational study

H Gomez - … Transactions of the Royal Society A, 2020 - royalsocietypublishing.org
Although cancerous tumours usually originate from a single cell, they normally evolve into a
remarkably heterogeneous agglomeration of cells. Heterogeneity is a pervasive and almost …

[图书][B] Mathematical modelling and biomechanics of the brain

C Drapaca, S Sivaloganathan - 2019 - Springer
The brain is one of the most important organs in the human body and serves as the control
center for the nervous system supporting all the required functions of the body parts and …

[HTML][HTML] What mathematical models can or cannot do in glioma description and understanding

A Perrillat-Mercerot, A Miranville… - … Dynamical Systems-S, 2020 - aimsciences.org
Our aim in this article is not to provide a review of the existing literature but to make a critical
analysis on glioma behavior mathematical modeling. We present here mathematical …