circRNA-miRNA-mRNA in breast cancer

M Zhang, X Bai, X Zeng, J Liu, F Liu, Z Zhang - Clinica Chimica Acta, 2021 - Elsevier
Among cancers, breast cancer has the highest incidence rate among women and poses a
tremendous threat to women's health. Messenger RNA (mRNA), microRNA (miRNA) and …

[HTML][HTML] Circular RNAs: new layer of complexity evading breast cancer heterogeneity

A Dawoud, ZI Zakaria, HH Rashwan… - Non-Coding RNA …, 2023 - Elsevier
Advances in high-throughput sequencing techniques and bioinformatic analysis have
refuted the “junk” RNA hypothesis that was claimed against non-coding RNAs (ncRNAs) …

CircRNA circ-PDCD11 promotes triple-negative breast cancer progression via enhancing aerobic glycolysis

Z Xing, R Wang, X Wang, J Liu, M Zhang, K Feng… - Cell death …, 2021 - nature.com
Well-described evidence has demonstrated the critical roles of aerobic glycolysis in triple-
negative breast cancer (TNBC) oncotherapy. Moreover, next-generation high-throughput …

Exosomal circular RNAs: New player in breast cancer progression and therapeutic targets

BM Hussen, S Mohamadtahr, SR Abdullah… - Frontiers in …, 2023 - frontiersin.org
Breast cancer is the most prevalent type of malignancy among women. Exosomes are
extracellular vesicles of cell membrane origin that are released via exocytosis. Their cargo …

[HTML][HTML] The biogenesis, function and clinical significance of circular RNAs in breast cancer

Y Zeng, Y Zou, G Gao, S Zheng, S Wu… - Cancer biology & …, 2022 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) are noncoding RNAs that form covalently closed loop structures.
CircRNAs are dysregulated in cancer and play key roles in tumorigenesis, diagnosis, and …

Emerging role of circular RNAs in breast cancer

S Ghafouri-Fard, BM Hussen, M Taheri… - Pathology-Research and …, 2021 - Elsevier
Circular RNAs (cirRNAs) are generally considered as non-coding RNAs which can act as
molecular sponges for miRNAs, exert regulatory roles in transcription or splicing, and …

Triple-negative breast cancer: Identification of circRNAs with efficacy in preclinical in vivo models

UH Weidle, F Birzele - Cancer Genomics & Proteomics, 2023 - cgp.iiarjournals.org
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer with
insufficient options for therapy. In order to identify new targets and treatment modalities we …

Exosomal circRHCG promotes breast cancer metastasis via facilitating M2 polarization through TFEB ubiquitination and degradation

H Shen, J Xu, W Zhang, Q Chen, Z Zhu… - NPJ Precision …, 2024 - nature.com
Triple-negative breast cancer (TNBC) is a highly aggressive cancer with distant metastasis.
Accumulated evidence has demonstrated that exosomes are involved in TNBC metastasis …

Circular RNAs: their role in the pathogenesis and orchestration of breast cancer

X He, T Xu, W Hu, Y Tan, D Wang, Y Wang… - Frontiers in Cell and …, 2021 - frontiersin.org
As one of the most frequently occurring malignancies in women, breast cancer (BC) is still
an enormous threat to women all over the world. The high mortality rates in BC patients are …

The dual role of circular RNAs as miRNA sponges in breast cancer and colon cancer

J Huang, S Yu, L Ding, L Ma, H Chen, H Zhou, Y Zou… - Biomedicines, 2021 - mdpi.com
Breast cancer (BC) and colon cancer (CRC) are the two most deadly cancers in the world.
These cancers partly share the same genetic background and are partially regulated by the …