Flavonoids: A complementary approach to conventional therapy of COVID-19?

J Solnier, JP Fladerer - Phytochemistry Reviews, 2021 - Springer
COVID-19, the highly contagious novel disease caused by SARS-CoV-2, has become a
major international concern as it has spread quickly all over the globe. However, scientific …

Lipid-based delivery systems for flavonoids and flavonolignans: liposomes, nanoemulsions, and solid lipid nanoparticles

S Ranjbar, A Emamjomeh, F Sharifi, A Zarepour… - Pharmaceutics, 2023 - mdpi.com
Herbal chemicals with a long history in medicine have attracted a lot of attention.
Flavonolignans and flavonoids are considered as two classes of the above-mentioned …

Food containing bioactive flavonoids and other phenolic or sulfur phytochemicals with antiviral effect: can we design a promising diet against COVID-19?

M Ghidoli, F Colombo, S Sangiorgio, M Landoni… - Frontiers in …, 2021 - frontiersin.org
Since in late 2019, when the coronavirus 2 (SARS-CoV-2) pathogen of coronavirus disease
2019 (COVID-19) started to spread all over the world, causing the awful global pandemic we …

Flavonoids as a therapeutical option for the treatment of thrombotic complications associated with COVID‐19

JP Quintal Martinez… - Phytotherapy …, 2023 - Wiley Online Library
The SARS‐CoV‐2 outbreak has been one of the largest public health crises globally, while
thrombotic complications have emerged as an important factor contributing to mortality …

Phytochemical Analysis of the Methanolic Extract and Essential Oil from Leaves of Industrial Hemp Futura 75 Cultivar: Isolation of a New Cannabinoid Derivative and …

S De Vita, C Finamore, MG Chini, G Saviano… - Plants, 2022 - mdpi.com
Cannabis sativa L. is a plant belonging to the Cannabaceae family, cultivated for its
psychoactive cannabinoid (Δ9-THC) concentration or for its fiber and nutrient content in …

Bioactive natural compounds with antiplatelet and anticoagulant activity and their potential role in the treatment of thrombotic disorders

S Lamponi - Life, 2021 - mdpi.com
Natural anticoagulant drugs can be obtained from plants, rich in secondary bioactive
metabolites which, in addition to being effective antioxidants, also possess anticoagulant …

MILCDock: machine learning enhanced consensus docking for virtual screening in drug discovery

CJ Morris, JA Stern, B Stark… - Journal of Chemical …, 2022 - ACS Publications
Molecular docking tools are regularly used to computationally identify new molecules in
virtual screening for drug discovery. However, docking tools suffer from inaccurate scoring …

A comprehensive strategy integrating metabolomics with multiple chemometric for discovery of function related active markers for assessment of foodstuffs: A case of …

Y Cui, K Du, S Hou, R Yang, L Qi, J Li, Y Chang - Food Chemistry, 2022 - Elsevier
There is a growing demand for functional foodstuffs naturally rich in nutrients and bioactive
compounds associated with putative health benefits. This study followed a strategy …

Virtual screening and biological activity evaluation of novel efflux pump inhibitors targeting AdeB

Y Tuo, Y Tang, R Yang, XM Zhao, M Luo, X Zhou… - International Journal of …, 2023 - Elsevier
The AdeABC efflux pump is an important mechanism causing multidrug resistance in
Acinetobacter baumannii, and its main component AdeB can recognize carbapenems …

Ecological roles of secondary metabolites of Saposhnikovia divaricata in adaptation to drought stress

S Cao, L Shi, Y Shen, L He, X Meng - PeerJ, 2022 - peerj.com
Saposhnikovia divaricata is a traditional Chinese herb that mainly grows in arid grasslands
and strongly adapts to various stresses. Drought is not only a major abiotic stress factor but …