PURPOSE Benefit of lung cancer screening using low-dose computed tomography (LDCT)
in reducing lung cancer–specific and all-cause mortality is unclear. We undertook a meta …

As randomized trials in the USA and Europe have convincingly demonstrated efficacy of
lung cancer screening by computed tomography (CT), European countries are discussing …

Serine protease inhibitor Kazal type 1 (SPINK1) plays a role in protecting the pancreas
against premature activation of trypsinogen and is involved in cancer progression. SPINK1 …

Lung cancer, chronic obstructive pulmonary disease, and cardiovascular disease are highly
prevalent in the general population and expected to cause most deaths by 2050. For these …

Overdiagnosis is a major potential harm of lung cancer screening; knowing its potential
magnitude helps to optimize screening eligibility criteria. The German Lung Screening …

Importance Malignancy prediction models based on participant-related characteristics and
imaging parameters from low-dose computed tomography (CT) may improve decision …

We aimed to explore the underlying reasons that estimates of overdiagnosis vary across and
within low‐dose computed tomography (LDCT) lung cancer screening trials. We conducted …

Background Changes in smoking habits and predictors of smoking cessation were
examined in the randomized ITALUNG lung cancer screening trial. Methods In three centers …

Lung adenocarcinoma (LUAD), as a form of non‐small cell lung cancer (NSCLC), is the
most frequently diagnosed lung cancer worldwide. To date, a few biomarkers have been …

Lung cancer (LC) is the leading cause of cancer-related death worldwide, mostly because
the lack of a screening program so far. Although smoking cessation has a central role in LC …