Since the clinical introduction of magnetic resonance imaging (MRI), the chest has been one
of its most challenging applications, and many physicists and radiologists have tried since …

Background We sought to develop a proteomics-based risk model for lung cancer and
evaluate its risk-discriminatory performance in comparison with a smoking-based risk model …

Importance Current eligibility criteria for lung cancer (LC) screening are derived from
randomised controlled trials and primarily based on age and smoking history. However, the …

Despite the high prevalence and mortality of lung cancer and proven effectiveness of low-
dose computed tomography (LDCT) to reduce mortality, Germany still lacks a national …

Background Trials in the USA and Europe have convincingly demonstrated the efficacy of
screening by low-dose computed tomography (LDCT) as a means to lower lung cancer …

Abstract The Lung Screening Study was a multicenter controlled feasibility trial that
randomly assigned subjects to undergo two rounds of screening with either low-dose spiral …

Chronic obstructive pulmonary disease (COPD) and lung cancer are common global causes
of morbidity and mortality. Because both diseases share several predisposing risks, the 2 …

Lung cancer remains the most significant cause of cancer death, accounting for about 20%
of all cancer-related mortality. A significant reason for this is delayed diagnosis, either due to …

Abstract The Italian Association of Medical Oncology (AIOM) has developed clinical practice
guidelines for the diagnosis and treatment of patients with early and locally advanced non …

Background Tumor-associated autoantibodies are considered promising markers for early
lung cancer detection; so far, however, their capacity to detect cancer has been tested …