Menopausal vasomotor symptoms and plasma Alzheimer disease biomarkers

RC Thurston, P Maki, Y Chang, M Wu… - American journal of …, 2024 - Elsevier
Background Identifying risk factors for Alzheimer disease in women is important as women
compose two-thirds of individuals with Alzheimer disease. Previous work links vasomotor …

CD33 rs2455069 SNP: correlation with Alzheimer's disease and hypothesis of functional role

F Tortora, A Rendina, A Angiolillo… - International Journal of …, 2022 - mdpi.com
The CD33 gene encodes for a member of the sialic-acid-binding immunoglobulin-type lectin
(Siglec) family, and is one of the top-ranked Alzheimer's disease (AD) risk genes identified …

Whole genome methylation sequencing in blood identifies extensive differential DNA methylation in late‐onset dementia due to Alzheimer's disease

C Breen, LA Papale, LR Clark… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION DNA microarray‐based studies report differentially methylated positions
(DMPs) in blood between late‐onset dementia due to Alzheimer's disease (AD) and …

CDiP technology for reverse engineering of sporadic Alzheimer's disease

T Kondo, Y Yada, T Ikeuchi, H Inoue - Journal of Human Genetics, 2023 - nature.com
Alzheimer's disease (AD) is a neurodegenerative disease that causes cognitive impairment
for which neither treatable nor preventable approaches have been confirmed. Although …

Evaluation of common and rare variants of Alzheimer's disease-causal genes in Parkinson's disease

Q Zeng, H Pan, Y Zhao, Y Wang, Q Xu, J Tan… - Parkinsonism & Related …, 2022 - Elsevier
Introduction Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common
neurodegenerative diseases in the elderly. Recently, some variants of AD-causal genes …

Apolipoprotein E and Alzheimer's disease pathology in African American older adults

SK Royse, BE Snitz, AV Hill, AC Reese, RE Roush… - Neurobiology of …, 2024 - Elsevier
Abstract The apolipoprotein-E4 (APOE* 4) and apolipoprotein-E2 (APOE* 2) alleles are
more common in African American versus non-Hispanic white populations, but relationships …

Genomics of Brain Disorders 4.0

R Cacabelos - International Journal of Molecular Sciences, 2024 - mdpi.com
Several historic, scientific events have occurred in the decade 2013–2023, in particular the
COVID-19 pandemic. This massive pathogenic threat, which has affected the world's …

The power of representation: Statistical analysis of diversity in US Alzheimer's disease genetics data

D Xue, EE Blue, MP Conomos… - Alzheimer's & Dementia …, 2024 - Wiley Online Library
INTRODUCTION Alzheimer's disease (AD) is a complex disease influenced by genetics and
environment. More than 75 susceptibility loci have been linked to late‐onset AD, but most of …

Towards a Unitary Hypothesis of Alzheimer's Disease Pathogenesis

E Area-Gomez, EA Schon - Journal of Alzheimer's Disease, 2024 - content.iospress.com
The “amyloid cascade” hypothesis of Alzheimer's disease (AD) pathogenesis invokes the
accumulation in the brain of plaques (containing the amyloid-β protein precursor [AβPP] …

Carotid intima media thickness and white matter hyperintensity volume among midlife women

RC Thurston, M Wu, E Barinas‐Mitchell… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Carotid atherosclerosis may be associated with brain white matter
hyperintensities (WMH). Few studies consider women at midlife, a critical time for women's …