Magnesium is an essential element of life, involved in the regulation of metabolism and
homeostasis of all the tissues. It also regulates immunological functions, acting on the cells …

In patients with diabetes, myocardial fibrosis may contribute to the pathogenesis of heart
failure and arrhythmogenesis, increasing ventricular stiffness and delaying conduction …

Major depressive disorder (MDD) is the most prevalent psychiatric disorder worldwide and
severely limits psychosocial function and quality of life, but no effective medication is …

Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …

Exploring the molecular mechanisms that prevent inflammation during caloric restriction may
yield promising therapeutic targets. During fasting, activation of the nuclear receptor …

Calcium is the most abundant mineral in the human body and is central to many
physiological processes, including immune system activation and maintenance. Studies …

We investigated the association of redox regulator Nuclear factor erythroid 2-related factor 2
(Nrf2) and inflammatory cytokines as well as clinical remission in patients with recent onset …

Background CD33 is a membrane receptor containing a lectin domain and a cytoplasmic
immunoreceptor tyrosine-based inhibitory motif (ITIM) that is able to inhibit cytokine …

Lung ischaemia–reperfusion-induced oedema (LIRE) is a life-threatening condition that
causes pulmonary oedema induced by endothelial dysfunction. Here we show that lungs …

Diabetes mellitus, a debilitating chronic disease, affects~ 100 million people. Peripheral
neuropathy is one of the most common early complications of diabetes in~ 66% of these …