Can we predict T cell specificity with digital biology and machine learning?
Recent advances in machine learning and experimental biology have offered breakthrough
solutions to problems such as protein structure prediction that were long thought to be …
solutions to problems such as protein structure prediction that were long thought to be …
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
Over the past year, numerous studies in the peer reviewed and preprint literature have
reported on the virological, epidemiological and clinical characteristics of the coronavirus …
reported on the virological, epidemiological and clinical characteristics of the coronavirus …
[HTML][HTML] Multiple early factors anticipate post-acute COVID-19 sequelae
Post-acute sequelae of COVID-19 (PASC) represent an emerging global crisis. However,
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …
quantifiable risk factors for PASC and their biological associations are poorly resolved. We …
Immunopathological signatures in multisystem inflammatory syndrome in children and pediatric COVID-19
Abstract Pediatric Coronavirus Disease 2019 (pCOVID-19) is rarely severe; however, a
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …
minority of children infected with severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] Impact of SARS-CoV-2 variants on the total CD4+ and CD8+ T cell reactivity in infected or vaccinated individuals
The emergence of SARS-CoV-2 variants with evidence of antibody escape highlight the
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …
importance of addressing whether the total CD4+ and CD8+ T cell recognition is also …
Immunogenicity of Ad26. COV2. S vaccine against SARS-CoV-2 variants in humans
G Alter, J Yu, J Liu, A Chandrashekar, EN Borducchi… - Nature, 2021 - nature.com
Abstract The Ad26. COV2. S vaccine,–has demonstrated clinical efficacy against
symptomatic COVID-19, including against the B. 1.351 variant that is partially resistant to …
symptomatic COVID-19, including against the B. 1.351 variant that is partially resistant to …
Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases
T cells are involved in control of SARS-CoV-2 infection. To establish the patterns of
immunodominance of different SARS-CoV-2 antigens and precisely measure virus-specific …
immunodominance of different SARS-CoV-2 antigens and precisely measure virus-specific …
[PDF][PDF] COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing
Kwok-Yung Yuen Email: kyyuen@ hku. hk Phone number:(852)-22552413 Carol Yu Centre
for Infection, State Key Laboratory of Emerging Infectious Diseases, Department of …
for Infection, State Key Laboratory of Emerging Infectious Diseases, Department of …
Combination anti-HIV antibodies provide sustained virological suppression
MC Sneller, J Blazkova, JS Justement, V Shi… - Nature, 2022 - nature.com
Antiretroviral therapy is highly effective in suppressing human immunodeficiency virus (HIV).
However, eradication of the virus in individuals with HIV has not been possible to date …
However, eradication of the virus in individuals with HIV has not been possible to date …
Understanding T cell responses to COVID-19 is essential for informing public health strategies
S Vardhana, L Baldo, WG Morice, EJ Wherry - Science immunology, 2022 - science.org
Durable T cell responses to SARS-CoV-2 antigens after infection or vaccination improve
immune-mediated viral clearance. To date, population-based surveys of COVID-19 adaptive …
immune-mediated viral clearance. To date, population-based surveys of COVID-19 adaptive …