The SARS‐CoV‐2 spike glycoprotein directly binds exogeneous sialic acids: A NMR view
L Unione, MJ Moure, MP Lenza, I Oyenarte… - Angewandte …, 2022 - Wiley Online Library
The interaction of the SARS CoV2 spike glycoprotein with two sialic acid‐containing
trisaccharides (α2, 3 and α2, 6 sialyl N‐acetyllactosamine) has been demonstrated by NMR …
trisaccharides (α2, 3 and α2, 6 sialyl N‐acetyllactosamine) has been demonstrated by NMR …
Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
RQ Wu, XM Lao, DP Chen, H Qin, M Mu, WJ Cao… - Immunity, 2023 - cell.com
The reinvigoration of anti-tumor T cells in response to immune checkpoint blockade (ICB)
therapy is well established. Whether and how ICB therapy manipulates antibody-mediated …
therapy is well established. Whether and how ICB therapy manipulates antibody-mediated …
Structure-based neutralizing mechanisms for SARS-CoV-2 antibodies
Q Huang, X Han, J Yan - Emerging Microbes & Infections, 2022 - Taylor & Francis
The devastating economic and public health consequences caused by the COVID-19
pandemic have prompted outstanding efforts from the scientific community and …
pandemic have prompted outstanding efforts from the scientific community and …
[HTML][HTML] SARS-CoV-2 infection of phagocytic immune cells and COVID-19 pathology: Antibody-dependent as well as independent cell entry
O Matveeva, Y Nechipurenko, D Lagutkin… - Frontiers in …, 2022 - frontiersin.org
Our review summarizes the evidence that COVID-19 can be complicated by SARS-CoV-2
infection of immune cells. This evidence is widespread and accumulating at an increasing …
infection of immune cells. This evidence is widespread and accumulating at an increasing …
Powerful avidity with a limited valency for virus-attachment blockers on DC-SIGN: combining chelation and statistical rebinding with structural plasticity of the receptor
The C-type lectin receptor DC-SIGN has been highlighted as the coreceptor for the spike
protein of the SARS-CoV-2 virus. A multivalent glycomimetic ligand, Polyman26, has been …
protein of the SARS-CoV-2 virus. A multivalent glycomimetic ligand, Polyman26, has been …
[HTML][HTML] Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains
SM Roelle, N Shukla, AT Pham, AM Bruchez… - PLoS …, 2022 - journals.plos.org
Viral spillover from animal reservoirs can trigger public health crises and cripple the world
economy. Knowing which viruses are primed for zoonotic transmission can focus …
economy. Knowing which viruses are primed for zoonotic transmission can focus …
[HTML][HTML] Effects of N-glycan modifications on spike expression, virus infectivity, and neutralization sensitivity in ancestral compared to Omicron SARS-CoV-2 variants
S Lusvarghi, CB Stauft, R Vassell, B Williams… - PLoS …, 2023 - journals.plos.org
The SARS-CoV-2 spike glycoprotein has 22 potential N-linked glycosylation sites per
monomer that are highly conserved among diverse variants, but how individual glycans …
monomer that are highly conserved among diverse variants, but how individual glycans …
[HTML][HTML] Alveolar macrophages: Achilles' heel of SARS-CoV-2 infection
Z Wang, S Li, B Huang - Signal Transduction and Targeted Therapy, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has caused more than 6.3
million deaths to date. Despite great efforts to curb the spread of severe acute respiratory …
million deaths to date. Despite great efforts to curb the spread of severe acute respiratory …
[HTML][HTML] Myeloid C-type lectin receptors in innate immune recognition
CR e Sousa, S Yamasaki, GD Brown - Immunity, 2024 - cell.com
C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …
[HTML][HTML] The multifaceted roles of NLRP3-modulating proteins in virus infection
The innate immune response to viruses is critical for the correct establishment of protective
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …