The role of antigen-presenting cells in the pathogenesis of COVID-19

R Farzi, PS Aghbash, N Eslami, A Azadi… - … -Research and Practice, 2022 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is one of the three lethal coronavirus
outbreaks in the recent two decades and a serious threat to global health all over the world …

[HTML][HTML] Macrophages and monocytes:“Trojan Horses” in COVID-19

E Percivalle, JC Sammartino, I Cassaniti, E Arbustini… - Viruses, 2021 - mdpi.com
We aimed to explore whether variants of SARS-CoV-2 (Chinese-derived strain (D614,
lineage A), Italian strain PV10734 (D614G, lineage B. 1.1) and Alpha strain (lineage B. 1.1 …

[HTML][HTML] Uses and challenges of antiviral polyclonal and monoclonal antibody therapies

EB Struble, JMO Rawson, T Stantchev, D Scott… - Pharmaceutics, 2023 - mdpi.com
Viral diseases represent a major public health concerns and ever-present risks for
developing into future pandemics. Antiviral antibody therapeutics, either alone or in …

[HTML][HTML] Heparan sulfate and sialic acid in viral attachment: Two sides of the same coin?

IE Ramos-Martínez, E Ramos-Martínez… - International Journal of …, 2022 - mdpi.com
Sialic acids and heparan sulfates make up the outermost part of the cell membrane and the
extracellular matrix. Both structures are characterized by being negatively charged, serving …

S glycoprotein diversity of the Omicron variant

R Sarkar, M Lo, R Saha, S Dutta, M Chawla-Sarkar - MedRxiv, 2021 - medrxiv.org
On the backdrop of ongoing Delta variant infection and vaccine-induced immunity, the
emergence of the new Variant of Concern, the Omicron, has again fuelled the fears of …

[HTML][HTML] Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

R Marzi, J Bassi, C Silacci-Fregni, I Bartha, F Muoio… - Iscience, 2023 - cell.com
Memory B cells (MBCs) generate rapid antibody responses upon secondary encounter with
a pathogen. Here, we investigated the kinetics, avidity, and cross-reactivity of serum …

Pulmonary macrophages and SARS-Cov2 infection

CC Bain, AG Rossi, CD Lucas - International Review of Cell and Molecular …, 2022 - Elsevier
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to the largest global pandemic in living memory, with between 4.5 and 15M deaths globally …

Neurological pathophysiology of SARS‐CoV‐2 and pandemic potential RNA viruses: a comparative analysis

N Chakravarty, T Senthilnathan, S Paiola, P Gyani… - FEBS …, 2021 - Wiley Online Library
SARS‐CoV‐2 has infected hundreds of millions of people with over four million dead,
resulting in one of the worst global pandemics in recent history. Neurological symptoms …

[HTML][HTML] Persistent immune imprinting after XBB. 1.5 COVID vaccination in humans

MA Tortorici, A Addetia, AJ Seo, J Brown, KR Sprouse… - Biorxiv, 2023 - ncbi.nlm.nih.gov
Immune imprinting-also known as 'original antigenic sin'-describes how the first exposure to
a virus shapes the immunological outcome of subsequent exposures to antigenically related …

[HTML][HTML] SARS-CoV-2 Omicron variants reduce antibody neutralization and acquire usage of mouse ACE2

R Wang, Q Zhang, R Zhang, ZQ Aw, P Chen… - Frontiers in …, 2022 - frontiersin.org
Striking number of mutations found in the spike protein of recently emerged SARS-CoV-2
Omicron subvariants BA. 1, BA. 2, BA. 3 and BA. 4/5 has raised serious concerns regarding …