Influence of the environmental tonicity perturbations on the release of model compounds from large unilamellar vesicles (LUVs): A mechanistic investigation

IY Wu, N Škalko-Basnet, MP di Cagno - Colloids and Surfaces B …, 2017 - Elsevier
In this work, the influence of environmental tonicity perturbations on the size and release
kinetics of model markers from liposomes (calcein and rhodamine) was investigated. Large …

The Influence of Functional Carrier Particles (FCPs) on the molecular transport rate through the reconstructed bronchial mucus: In vitro studies

M Odziomek, TR Sosnowski, L Gradoń - Transport in Porous Media, 2015 - Springer
Mass transfer of deposited drug particles in the human lungs is an important factor in the
effective drug delivery by inhalation. This study is focused on the basic research related to …

Development, characterization and evidence of anti-endometriotic activity of Phytocannabinoid-Rich nanoemulsions

TN Barradas, SA Cardoso, P de Castro Grimaldi… - International Journal of …, 2023 - Elsevier
During the last decades, the cannabinoid research for therapeutic purposes has been
rapidly advancing, with an ever-growing body of evidence of beneficial effects for a wide sort …

Mechanistic study on hydrodynamics in the mini-scale biphasic dissolution model and its influence on in vitro dissolution and partitioning

K Locher, JM Borghardt, H Wachtel, KJ Schaefer… - European Journal of …, 2018 - Elsevier
Biphasic dissolution models were proposed to provide good predictive power for in vivo
absorption kinetics. However, up to date the impact of hydrodynamics in mini-scale models …

Effect of crystallinity of bio-based polymers on compatibility and the tortuous path model of cellulose-based industrial products

N Sundar, A Pavithra, S Ananda Kumar - Biomass Conversion and …, 2023 - Springer
Polylactic acid (PLA) is chosen as a coating material on industrial Kraft paper substrates to
impart a barrier against air, grease, and water. This is an excellent initiative to replace the …

Evaluation of topical econazole nitrate formulations with potential for treating Raynaud's phenomenon

D Bahl, S Daftardar, R Devi Bachu… - Pharmaceutical …, 2019 - Taylor & Francis
The purpose of this work was to design and characterize a topical formulation of econazole
nitrate (EN) with potential for treating Raynaud's phenomenon (RP). Four topical dosage …

Overcoming the mucus barrier

JS Mortensen, MB Stie… - Organelle and …, 2021 - taylorfrancis.com
It is increasingly recognized that the mucus lining all mucosal surfaces in the body may
comprise a barrier to drug delivery. Numerous approaches are currently applied to …

Effects of ε‐viniferin, a dehydrodimer of resveratrol, on transepithelial active ion transport and ion permeability in the rat small and large intestinal mucosa

SI Karaki, J Ishikawa, Y Tomizawa… - Physiological …, 2016 - Wiley Online Library
Abstract ε‐Viniferin is a dehydrodimer of resveratrol, a polyphenol synthesized in many
plants, including grapevine. The present study investigated the effects of ε‐viniferin and …

Measurement of Transcellular Transport Rates and Intracellular Drug Sequestration in the Presence of an Extracellular Concentration Gradient

KA Min, GR Rosania - Quantitative Analysis of Cellular Drug Transport …, 2021 - Springer
In order for a drug to be effective and ultimately successful, it must first gain access to its
molecular target at a desired site of action. Conventionally, for the purpose of high …

Exploring drug diffusion through a membrane: A physical chemistry experiment for health and life sciences undergraduate students

IAC Ribeiro, CMC Faustino, RC Guedes… - Journal of Chemical …, 2015 - ACS Publications
The transport of molecules across biological membranes are critical for most cellular
processes. Membrane permeability is also a key determinant for drug absorption …