Vectors expressing the first 58 amino acids of the hepatitis C virus (HCV) nucleocapsid
alone or as a fusion protein with the middle (pre-S2 and S) or major (S) surface antigens of …

A candidate DNA vaccine expressing dengue virus type 1 pre-membrane and envelope
proteins was used to immunize rhesus macaques. Monkeys were immunized …

DNA vaccines, with which the antigen is synthesized in vivo after direct introduction of its
encoding sequences, offer a unique method of immunization that may overcome many of the …

Liposomes have been widely used to enhance the immune response. In the present
investigation, we studied their in vivo immunomodulation of an HIV-1-specific DNA vaccine …

The potential for eliciting humoral and cytotoxic T lymphocyte (CTL) responses to HIV-1
gp120 by gene gunbased DNA immunization in mice was examined. We speculated that the …

This article reviews advances in the field of human immunodeficiency virus type 1 (HIV-1)
and AIDS vaccine development over the last decade, with an emphasis on the DNA …

We describe an improved genetic immunization strategy for eliciting a full spectrum of anti-
hepatitis C virus (HCV) envelope 2 (E2) glycoprotein responses in mammals through …

The potential contribution of a plasmid DNA construct to vaccine-elicited protective immunity
was explored in the simian immunodeficiency virus (SIV)/macaque model of AIDS. Making …

Direct DNA inoculation is the basis for a new technology that has been successfully used for
in vivo induction of both humoral and cellular immune responses. However, the …

DNA-based immunizations have been used to analyze the ability of DNA-expressed
hemagglutinin (HA) and nucleoprotein (NP) to protect BALB/c mice against a homologous …