Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects

C Ornelas, D Astruc - Pharmaceutics, 2023 - mdpi.com
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Quinoline-based antimalarial hybrid compounds

S Vandekerckhove, M D'hooghe - Bioorganic & medicinal chemistry, 2015 - Elsevier
Quinoline-containing compounds, such as quinine and chloroquine, have a long-standing
history as potent antimalarial agents. However, the increasing resistance of the Plasmodium …

Synthesis, structural characterization, DFT calculations, molecular docking, and molecular dynamics simulations of a novel ferrocene derivative to unravel its potential …

MM Hammoud, M Khattab, M Abdel-Motaal… - Journal of …, 2023 - Taylor & Francis
In this article, we describe a set of subsequent five-steps chemical reactions to synthesize a
ferrocene derivative named 1-(5-(diphenylphosphaneyl) cyclopenta-1, 3-dien-1-yl) ethyl) …

Ferrocene derivatives as anti-infective agents

BS Ludwig, JDG Correia, FE Kühn - Coordination Chemistry Reviews, 2019 - Elsevier
Infectious diseases like malaria, tuberculosis or HIV are among the leading causes of death
worldwide according to WHO estimations. Nevertheless, the fight against infectious diseases …

Recent advances in the development of ferrocene based electroactive small molecules for cation recognition: A comprehensive review of the years 2010–2020

A Pal, SR Bhatta, A Thakur - Coordination Chemistry Reviews, 2021 - Elsevier
Cations are ubiquitous for biological systems and play a very critical role in our cellular level,
extracellular fluids (mostly monovalent cations) and in central nervous system …

Current scenario of ferrocene-containing hybrids for antimalarial activity

J Xiao, Z Sun, F Kong, F Gao - European Journal of Medicinal Chemistry, 2020 - Elsevier
Hybrid molecules have the potential to enhance the efficacy against both drug-sensitive and
drug-resistant organisms, and Ferroquine, a ferrocene hybrid, has demonstrated great …

New efficient artemisinin derived agents against human leukemia cells, human cytomegalovirus and Plasmodium falciparum: 2nd generation 1, 2, 4-trioxane …

C Reiter, T Fröhlich, M Zeino, M Marschall… - European journal of …, 2015 - Elsevier
In our ongoing search for highly active hybrid molecules exceeding their parent compounds
in anticancer, antimalaria as well as antiviral activity and being an alternative to the standard …

Medicinal utility of thiosemicarbazones with special reference to mixed ligand and mixed metal complexes: A Review

T Khan, S Raza, AJ Lawrence - Russian Journal of Coordination …, 2022 - Springer
Thiosemicarbazone complexes possess structural diversity and variable bonding patterns
and potential biological implications and ion sensing abilities. The ability of the transition …

Medicinal applications of coordination complexes

HS Mohammed, VD Tripathi - Journal of Physics: Conference …, 2020 - iopscience.iop.org
Coordination compounds and organometallics have very special place in chemistry due to
their different structural arrangements and application in various fields. They also play vital …

Stacking interactions of aromatic ligands in transition metal complexes

DP Malenov, SD Zarić - Coordination Chemistry Reviews, 2020 - Elsevier
In this review article we present all the recent research on stacking interactions of aromatic
ligands that coordinate to transition metals through their π-electrons (η-coordination). These …