Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

B Chen, P Yu, WN Chan, F Xie, Y Zhang… - … and Targeted Therapy, 2024 - nature.com
Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

The importance of selenium and zinc deficiency in cardiovascular disorders

P Gać, K Czerwińska, P Macek, A Jaremków… - Environmental …, 2021 - Elsevier
Cardiovascular diseases often linked with lifestyle are among the main causes of death,
especially in the elderly population. The role of trace elements in health and disease has …

The role of zinc homeostasis in the prevention of diabetes mellitus and cardiovascular diseases

Y Tamura - Journal of Atherosclerosis and Thrombosis, 2021 - jstage.jst.go.jp
Zinc is an essential micronutrient for human health and is involved in various biological
functions, such as growth, metabolism, and immune function. In recent years, research on …

Zinc as a biomarker of cardiovascular health

M Knez, M Glibetic - Frontiers in nutrition, 2021 - frontiersin.org
The importance of zinc (Zn) for cardiovascular health continuously gains recognition. As
shown earlier, compromised Zn homeostasis and prolonged inflammation are common …

Diabetic cardiomyopathy–Zinc preventive and therapeutic potentials by its anti-oxidative stress and sensitizing insulin signaling pathways

L Cai, Y Tan, S Watson, K Wintergerst - Toxicology and applied …, 2023 - Elsevier
Oxidative stress and insulin resistance are two key mechanisms for the development of
diabetic cardiomyopathy (DCM, cardiac remodeling and dysfunction). In this review, we …

[HTML][HTML] Preventing and controlling zinc deficiency across the life course: A call to action

NM Lowe, AG Hall, MR Broadley, J Foley, E Boy… - Advances in …, 2024 - Elsevier
Through diverse roles, zinc determines a greater number of critical life functions than any
other single micronutrient. Beyond the well-recognized importance of zinc for child growth …

The molecular basis for zinc bioavailability

AG Hall, JC King - International journal of molecular sciences, 2023 - mdpi.com
Zinc is an essential micronutrient, and its deficiency is perhaps the most prevalent and least
understood worldwide. Recent advances have expanded the understanding of zinc's unique …

[HTML][HTML] Diet in the management of type 2 diabetes: umbrella review of systematic reviews with meta-analyses of randomised controlled trials

E Szczerba, J Barbaresko, T Schiemann… - BMJ …, 2023 - ncbi.nlm.nih.gov
Diet in the management of type 2 diabetes: umbrella review of systematic reviews with meta-analyses
of randomised controlled trials - PMC Back to Top Skip to main content NIH NLM Logo Access …

Effect of zinc supplementation in the management of type 2 diabetes: A grading of recommendations assessment, development, and evaluation-assessed, dose …

K Ghaedi, D Ghasempour, M Jowshan… - Critical Reviews in …, 2023 - Taylor & Francis
The question of whether zinc supplementation may improve cardio-metabolic health in
patients with type 2 diabetes mellitus (T2DM) remains controversial and require further …

Effects of zinc supplementation on glycemic control and oxidative stress in experimental diabetes: A systematic review

MPSC Martins, ASSS Oliveira, VBL de Carvalho… - Clinical Nutrition …, 2022 - Elsevier
Introduction Diabetes mellitus (DM), an important public health problem worldwide, can
cause imbalances in the homeostasis of trace elements such as zinc (Zn). It is possible that …