Stress activates the hypothalamic–pituitary–adrenal (HPA) axis, which then modulates the
degree of adaptation and response to a later stressor. It is known that early-life stress can …

Mounting evidence connects non-alcoholic fatty liver disease (NAFLD) to chronic kidney
disease (CKD). We review emerging mechanistic links between NAFLD and CKD, including …

Betaine has been proven effective in treating nonalcoholic fatty liver disease (NAFLD) in
animal models, however, its molecular mechanisms remain elusive. The aims of this study …

High fructose intake causes metabolic syndrome, being an increased risk of chronic kidney
disease development in humans and animals. In this study, we examined the influence of …

One of the most important threats to global human health is the increasing incidences of
metabolic pathologies (including obesity, type 2 diabetes and non-alcoholic fatty liver …

Chronic arsenic exposure through drinking water threatens public health worldwide.
Although its multiorgan toxicity has been reported, the impact of chronic arsenic exposure on …

Purpose High fructose consumption provokes metabolic perturbations that result in chronic
low-grade inflammation and insulin resistance. Glucocorticoids, potent anti-inflammatory …

Purpose High-fructose consumption and chronic stress are both associated with metabolic
inflammation and insulin resistance. Recently, disturbed activity of energy sensor AMP …

The modern lifestyle brings both excessive fructose consumption and daily exposure to
stress which could lead to metabolic disturbances and type 2 diabetes. Muscles are …

Scope Intake of fructose‐sweetened beverages and chronic stress (CS) both increase risk of
cardiometabolic diseases. The aim is to investigate whether these factors synergistically …