Recent progress in DNA hybridization chain reaction strategies for amplified biosensing

H Chai, W Cheng, D Jin, P Miao - ACS Applied Materials & …, 2021 - ACS Publications
With the continuous development of DNA nanotechnology, various spatial DNA structures
and assembly techniques emerge. Hybridization chain reaction (HCR) is a typical example …

Analysis and biomedical applications of functional cargo in extracellular vesicles

F Qian, Z Huang, H Zhong, Q Lei, Y Ai, Z Xie, T Zhang… - ACS …, 2022 - ACS Publications
Extracellular vesicles (EVs) can facilitate essential communication among cells in a range of
pathophysiological conditions including cancer metastasis and progression, immune …

Integrating reliable Pt–S bond-mediated 3D DNA nanomachine with magnetic separation in a homogeneous electrochemical strategy for exosomal MicroRNA …

L Yang, H Guo, Q Gao, T Hou, J Zhang, X Liu… - Analytical …, 2023 - ACS Publications
Precise and sensitive analysis of exosomal microRNA (miRNA) is of great importance for
noninvasive early disease diagnosis, but it remains a great challenge to detect exosomal …

Dual-mode SERS and electrochemical detection of miRNA based on popcorn-like gold nanofilms and toehold-mediated strand displacement amplification reaction

H Zhou, J Zhang, B Li, J Liu, JJ Xu… - Analytical chemistry, 2021 - ACS Publications
MicroRNA (miRNA) has emerged as one of the ideal target biomarker analytes for cancer
detection because its abnormal expression is closely related to the occurrence of many …

DNA-tetrahedral-nanostructure-based entropy-driven amplifier for high-performance photoelectrochemical biosensing

H Li, M Han, X Weng, Y Zhang, J Li - ACS nano, 2021 - ACS Publications
In virtue of the inherent molecular recognition and programmability, DNA has recently
become the most promising for high-performance biosensors. The rationally engineered …

Cobalt metal-organic framework modified carbon cloth/paper hybrid electrochemical button-sensor for nonenzymatic glucose diagnostics

X Wei, J Guo, H Lian, X Sun, B Liu - Sensors and Actuators B: Chemical, 2021 - Elsevier
In the growing pandemic, family healthcare is widely concerned with the increase of medical
self-diagnosis away from the hospital. A cobalt metal-organic framework modified carbon …

Rapid electrochemical biosensor for sensitive profiling of exosomal microRNA based on multifunctional DNA tetrahedron assisted catalytic hairpin assembly

Y Zhang, X Zhang, B Situ, Y Wu, S Luo, L Zheng… - Biosensors and …, 2021 - Elsevier
Profiling of exosomal microRNA (exo-miRNA) is very important for cancer diagnosis and
treatment. However, rapid and sensitive determination the trace of exo-miRNA in clinical …

Mesoporous nanozyme-enhanced DNA tetrahedron electrochemiluminescent biosensor with three-dimensional walking nanomotor-mediated CRISPR/Cas12a for …

B Shen, L Li, C Liu, X Li, X Li, X Cheng, H Wu… - Analytical …, 2023 - ACS Publications
Exosomal microRNAs (exomiRNAs) have emerged as ideal biomarkers for early clinical
diagnostics. The accurate detection of exomiRNAs plays a crucial role in facilitating clinical …

Enzyme-free isothermal amplification strategy for the detection of tumor-associated biomarkers: A review

W Wang, Q Ge, X Zhao - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The detection of tumor-associated biomarkers contributes to personalized precision medical
treatment of cancer patients in early stage. Combined with nucleic acid amplification …

Ultrasensitive miRNA biosensor amplified by ladder hybridization chain reaction on triangular prism structured DNA

H Chai, J Zhu, Z Guo, Y Tang, P Miao - Biosensors and Bioelectronics, 2023 - Elsevier
Accurate and sensitive analysis of biomarkers is a promising way to provide comprehensive
physio-pathological information that is significant for early diagnosis of certain diseases …