N Craddock, P Sklar - The Lancet, 2013 - thelancet.com
Studies of families and twins show the importance of genetic factors affecting susceptibility to bipolar disorder and suggest substantial genetic and phenotypic complexity. Robust and …
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome- wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study (GWAS) including 20,352 cases and 31,358 controls of European descent …
Admixed populations are routinely excluded from genomic studies due to concerns over population structure. Here, we present a statistical framework and software package, Tractor …
We conducted a combined genome-wide association study (GWAS) of 7,481 individuals with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric GWAS …
C Coutton, J Escoffier, G Martinez… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Male infertility affects> 20 million men worldwide and represents a major health concern. Although multifactorial, male infertility has a strong genetic basis which has …
ME Talkowski, JA Rosenfeld, I Blumenthal… - Cell, 2012 - cell.com
Balanced chromosomal abnormalities (BCAs) represent a relatively untapped reservoir of single-gene disruptions in neurodevelopmental disorders (NDDs). We sequenced BCAs in …
Importance Genome-wide investigations provide systematic information regarding the neurobiology of psychiatric disorders. Objective To identify biological pathways that …
AW Charney, DM Ruderfer, EA Stahl, JL Moran… - Translational …, 2017 - nature.com
We performed a genome-wide association study of 6447 bipolar disorder (BD) cases and 12 639 controls from the International Cohort Collection for Bipolar Disorder (ICCBD). Meta …