Mirror-image proteins and peptides composed of D-amino acids are garnering increasing
attention as diagnostic agents and drug candidates due to their higher stability and lower …

Limited understanding of human proteoforms with complex posttranslational modifications
and the underlying mechanisms poses a major obstacle to research on human health and …

Mirror‐image proteins (D‐proteins) are useful in biomedical research for purposes such as
mirror‐image screening for D‐peptide drug discovery, but the chemical synthesis of many D …

Oncolytic peptides represented potential novel candidates for anticancer treatments
especially drug-resistant cancer cell lines. One of the most promising and extensively …

Developing “turn on” fluorescent probes was desirable for the detection of the effective
anticoagulant agent heparin in clinical applications. Through combining the aggregation …

The cyclization of polypeptides confers enhanced stability, specificity, binding affinity, and
cell permeability, making it a common feature in the backbone structure of natural products …

糖基化修饰在各类生理活动中起着非常关键的作用. 然而, 天然糖蛋白中糖型结构的微观异质性,
严重阻碍了糖型结构与糖蛋白功能之间构效关系的研究. 因此, 从分子层面精确控制糖蛋白结构 …

Comprehensive Summary The strategy of removable glycosylation modification was used to
overcome the low‐efficiency problem encountered in the chemical synthesis of the mirror …

Glycosylation modifications, extensively present on the surfaces of eukaryotic proteins as a
type of post-translational modification, hold significant physiological and pathological …

Oncolytic peptides represented potential novel candidates for anticancer treatments
especially drug-resistant cancer cell lines. One of the most promising and extensively …