[HTML][HTML] A cross-cohort analysis of autosomal DNA methylation sex differences in the term placenta
Background Human placental DNA methylation (DNAme) data is a valuable resource for
studying sex differences during gestation, as DNAme profiles after delivery reflect the …
studying sex differences during gestation, as DNAme profiles after delivery reflect the …
[HTML][HTML] Batch-effect detection, correction and characterisation in Illumina HumanMethylation450 and MethylationEPIC BeadChip array data
Background Genomic technologies can be subject to significant batch-effects which are
known to reduce experimental power and to potentially create false positive results. The …
known to reduce experimental power and to potentially create false positive results. The …
A review on epigenetic inheritance of experiences in humans
M Ghai, F Kader - Biochemical Genetics, 2022 - Springer
If genetics defines the inheritance of DNA, epigenetics aims to regulate and make it
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …
[HTML][HTML] Changes in DNA methylation from pre-to post-adolescence are associated with pubertal exposures
Background Adolescence is a period characterized by major biological development, which
may be associated with changes in DNA methylation (DNA-M). However, it is unknown to …
may be associated with changes in DNA methylation (DNA-M). However, it is unknown to …
[HTML][HTML] Sex chromosome complement and sex steroid signaling underlie sex differences in immunity to respiratory virus infection
RAJ Miller, AP Williams, S Kovats - Frontiers in Pharmacology, 2023 - frontiersin.org
Epidemiological studies have revealed sex differences in the incidence and morbidity of
respiratory virus infection in the human population, and often these observations are …
respiratory virus infection in the human population, and often these observations are …
[HTML][HTML] Who's afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data
Background Many human disease phenotypes manifest differently by sex, making the
development of methods for incorporating X and Y-chromosome data into analyses vital …
development of methods for incorporating X and Y-chromosome data into analyses vital …
[HTML][HTML] Periconceptional maternal mediterranean diet is associated with favorable offspring behaviors and altered CpG methylation of imprinted genes
JS House, M Mendez, RL Maguire… - Frontiers in cell and …, 2018 - frontiersin.org
Background: Maternal diet during pregnancy has been shown to influence the child neuro-
developmental outcomes. Studies examining effects of dietary patterns on offspring behavior …
developmental outcomes. Studies examining effects of dietary patterns on offspring behavior …
[HTML][HTML] Work-related stress and well-being in association with epigenetic age acceleration: a Northern Finland birth cohort 1966 study
Recent evidence indicates consistent association of low socioeconomic status with
epigenetic age acceleration, measured from DNA methylation. As work characteristics and …
epigenetic age acceleration, measured from DNA methylation. As work characteristics and …
[HTML][HTML] Genome-wide methylation data mirror ancestry information
Background Genetic data are known to harbor information about human demographics, and
genotyping data are commonly used for capturing ancestry information by leveraging …
genotyping data are commonly used for capturing ancestry information by leveraging …
[HTML][HTML] BayesCCE: a Bayesian framework for estimating cell-type composition from DNA methylation without the need for methylation reference
We introduce a Bayesian semi-supervised method for estimating cell counts from DNA
methylation by leveraging an easily obtainable prior knowledge on the cell-type composition …
methylation by leveraging an easily obtainable prior knowledge on the cell-type composition …