[HTML][HTML] Roles and functions of SARS-CoV-2 proteins in host immune evasion
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades the host immune
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
system through a variety of regulatory mechanisms. The genome of SARS-CoV-2 encodes …
[HTML][HTML] SARS-CoV-2 and the host cell: a tale of interactions
M Pizzato, C Baraldi, G Boscato Sopetto… - Frontiers in …, 2022 - frontiersin.org
The ability of a virus to spread between individuals, its replication capacity and the clinical
course of the infection are macroscopic consequences of a multifaceted molecular …
course of the infection are macroscopic consequences of a multifaceted molecular …
[HTML][HTML] The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …
[HTML][HTML] SARS-CoV-2 non-structural proteins and their roles in host immune evasion
Coronavirus disease 2019 (COVID-19) has caused an unprecedented global crisis and
continues to threaten public health. The etiological agent of this devastating pandemic …
continues to threaten public health. The etiological agent of this devastating pandemic …
[HTML][HTML] Interferon antagonists encoded by SARS-CoV-2 at a glance
The innate immune system is a powerful barrier against invading pathogens. Interferons
(IFNs) are a major part of the cytokine-mediated anti-viral innate immune response. After …
(IFNs) are a major part of the cytokine-mediated anti-viral innate immune response. After …
[HTML][HTML] Characterization of SARS-CoV-2 evasion: interferon pathway and therapeutic options
M Znaidia, C Demeret, S van der Werf, AV Komarova - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …
[HTML][HTML] Type I interferons in COVID-19 pathogenesis
Simple Summary The innate antiviral immune response is essential to limit virus replication
at early stages of infection, thus preventing viral spread and pathogenesis. Nevertheless …
at early stages of infection, thus preventing viral spread and pathogenesis. Nevertheless …
[HTML][HTML] SARS-CoV-2 spike antagonizes innate antiviral immunity by targeting interferon regulatory factor 3
RS Freitas, TF Crum, K Parvatiyar - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Corona virus disease 2019 (COVID-19) pathogenesis is intimately linked to the severe acute
respiratory syndrome corona virus 2 (SARS-CoV-2) and disease severity has been …
respiratory syndrome corona virus 2 (SARS-CoV-2) and disease severity has been …
[HTML][HTML] SARS-CoV-2-mediated evasion strategies for antiviral interferon pathways
SJ Oh, OS Shin - Journal of Microbiology, 2022 - Springer
With global expansion of the COVID-19 pandemic and the emergence of new variants,
extensive efforts have been made to develop highly effective antiviral drugs and vaccines …
extensive efforts have been made to develop highly effective antiviral drugs and vaccines …
RNA-dependent RNA polymerase of SARS-CoV-2 regulate host mRNA translation efficiency by hijacking eEF1A factors
H Gan, X Zhou, Q Lei, L Wu, J Niu, Q Zheng - Biochimica et Biophysica Acta …, 2024 - Elsevier
The RNA-dependent RNA polymerase (NSP12) of COVID-19 plays a significant role in the
viral infection process, which promotes viral RNA replication by cooperating with NSP7 and …
viral infection process, which promotes viral RNA replication by cooperating with NSP7 and …