Honey: an immunomodulator in wound healing

J Majtan - Wound Repair and Regeneration, 2014 - Wiley Online Library
Honey is a popular natural product that is used in the treatment of burns and a broad
spectrum of injuries, in particular chronic wounds. The antibacterial potential of honey has …

TREM-1 modulation strategies for sepsis

S Siskind, M Brenner, P Wang - Frontiers in Immunology, 2022 - frontiersin.org
The triggering receptor expressed on myeloid cells-1 (TREM-1) is a pattern recognition
receptor, which can be upregulated in inflammatory diseases as an amplifier of immune …

Role of the gut microbiome in the development of atherosclerotic cardiovascular disease

A Al Samarraie, M Pichette, G Rousseau - International Journal of …, 2023 - mdpi.com
Atherosclerotic cardiovascular disease (ASCVD) is the primary cause of death globally, with
nine million deaths directly attributable to ischemic heart diseases in 2020. Since the last …

Effects of particulate matter on inflammatory markers in the general adult population

DH Tsai, N Amyai, P Marques-Vidal, JL Wang… - Particle and fibre …, 2012 - Springer
Background Particulate air pollution is associated with increased risk of cardiovascular
disease and stroke. Although the precise mechanisms underlying this association are still …

Bench-to-bedside review: The inflammation-perpetuating pattern-recognition receptor RAGE as a therapeutic target in sepsis

C Bopp, A Bierhaus, S Hofer, A Bouchon, PP Nawroth… - Critical Care, 2008 - Springer
Sepsis still represents an important clinical and economic challenge for intensive care units.
Severe complications like multi-organ failure with high mortality and the lack of specific …

Is severe visceral leishmaniasis a systemic inflammatory response syndrome? A case control study

CHN Costa, GL Werneck, DL Costa… - Revista da Sociedade …, 2010 - SciELO Brasil
INTRODUCTION: The objective of the study is to identify the main risk factors for death by
New World visceral leishmaniasis and establish a coherent pathogenic substrate of severe …

Aminoguanidine affects systemic and lung inflammation induced by lipopolysaccharide in rats

S Saadat, F Beheshti, VR Askari, M Hosseini… - Respiratory …, 2019 - Springer
Background Nitric oxide is a mediator of potential importance in numerous physiological and
inflammatory processes in the lung. Aminoguanidine (AG) has been shown to have anti …

Link between macrophage migration inhibitory factor and cellular redox regulation

M Thiele, J Bernhagen - Antioxidants & redox signaling, 2005 - liebertpub.com
Macrophage migration inhibitory factor (MIF) is an evolutionary conserved 12.5-kDa protein
mediator with multiple functions in innate and acquired immunity. Upon leaderless secretion …

Evaluation of analgesic and anti-inflammatory activities and molecular docking analysis of steroidal lactones from Datura stramonium L.

G Chandan, C Kumar, P Chibber, A Kumar, G Singh… - Phytomedicine, 2021 - Elsevier
Background Datura stramonium L. is widely used across the world for its therapeutic
potential to treat inflammatory disorders. The current work was designed to isolate and …

To what extent are the terminal stages of sepsis, septic shock, systemic inflammatory response syndrome, and multiple organ dysfunction syndrome actually driven by …

DB Kell, E Pretorius - Seminars in thrombosis and hemostasis, 2018 - thieme-connect.com
A well-established development of increasing disease severity leads from sepsis through
systemic inflammatory response syndrome, septic shock, multiple organ dysfunction …