Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies

B Pardini, AA Sabo, G Birolo, GA Calin - Cancers, 2019 - mdpi.com
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …

Long non-coding RNAs as the critical regulators of epithelial mesenchymal transition in colorectal tumor cells: an overview

AA Hamidi, G Khalili-Tanha, Z Nasrpour Navaei… - Cancer cell …, 2022 - Springer
Colorectal cancer (CRC) is the second most common cause of cancer mortality and a major
health challenge worldwide. Despite advances in therapeutic and diagnostic methods, there …

Long noncoding RNA LINC00239 inhibits ferroptosis in colorectal cancer by binding to Keap1 to stabilize Nrf2

Y Han, X Gao, N Wu, Y Jin, H Zhou, W Wang… - Cell death & …, 2022 - nature.com
Ferroptosis, a novel regulated cell death induced by iron-dependent lipid peroxidation, plays
an important role in tumor development and drug resistance. Long noncoding RNAs …

LINC00941 promotes CRC metastasis through preventing SMAD4 protein degradation and activating the TGF-β/SMAD2/3 signaling pathway

N Wu, M Jiang, H Liu, Y Chu, D Wang, J Cao… - Cell Death & …, 2021 - nature.com
Abstrict LINC00941 is a novel lncRNA that has been found to exhibit protumorigenic and
prometastatic behaviors during tumorigenesis. However, its role in metastatic CRC remains …

MALAT1 is associated with poor response to oxaliplatin-based chemotherapy in colorectal cancer patients and promotes chemoresistance through EZH2

P Li, X Zhang, H Wang, L Wang, T Liu, L Du… - Molecular cancer …, 2017 - AACR
A major reason for oxaliplatin chemoresistance in colorectal cancer is the acquisition of
epithelial–mesenchymal transition (EMT) in cancer cells. The long noncoding RNA …

Long non-coding RNA H19 confers 5-Fu resistance in colorectal cancer by promoting SIRT1-mediated autophagy

M Wang, D Han, Z Yuan, H Hu, Z Zhao, R Yang… - Cell death & …, 2018 - nature.com
Chemotherapy failure is the major cause of recurrence and poor prognosis in colorectal
cancer (CRC) patients. The role of the differentially expressed lncRNAs in 5-Fluorouracil …

LncRNA SNHG7 sponges miR-216b to promote proliferation and liver metastasis of colorectal cancer through upregulating GALNT1

Y Shan, J Ma, Y Pan, J Hu, B Liu, L Jia - Cell death & disease, 2018 - nature.com
Accumulating evidence suggests long noncoding RNAs (lncRNAs) play an important role in
cancer progression. However, the function of lncRNA SNHG7 in colorectal cancer (CRC) …

LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2

M Xu, X Xu, B Pan, X Chen, K Lin, K Zeng, X Liu, T Xu… - Molecular cancer, 2019 - Springer
Background Emerging studies suggest that long non-coding RNAs (lncRNAs) play crucial
roles in colorectal cancer (CRC). Here, we report a lncRNA, SATB2-AS1, which is …

Long non-coding RNA CASC11 interacts with hnRNP-K and activates the WNT/β-catenin pathway to promote growth and metastasis in colorectal cancer

Z Zhang, C Zhou, Y Chang, Z Zhang, Y Hu, F Zhang… - Cancer letters, 2016 - Elsevier
The abnormal expression of many long non-coding RNAs (lncRNAs) has been reported in
the progression of various tumors, and these lncRNAs can be useful as diagnostic indicators …

KATZLDA: KATZ measure for the lncRNA-disease association prediction

X Chen - Scientific reports, 2015 - nature.com
Accumulating experimental studies have demonstrated important associations between
alterations and dysregulations of lncRNAs and the development and progression of various …