NETosis: sculpting tumor metastasis and immunotherapy

Y Hu, H Wang, Y Liu - Immunological Reviews, 2024 - Wiley Online Library
The process of neutrophil extracellular traps (NETs) formation, called NETosis, is a peculiar
death modality of neutrophils, which was first observed as an immune response against …

A new hope? Possibilities of therapeutic IgA antibodies in the treatment of inflammatory lung diseases

F Bohländer - Frontiers in Immunology, 2023 - frontiersin.org
Inflammatory lung diseases represent a persistent burden for patients and the global
healthcare system. The combination of high morbidity,(partially) high mortality and limited …

Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs

P Weeratunga, L Denney, JA Bull, E Repapi… - Nature …, 2023 - nature.com
Single cell spatial interrogation of the immune-structural interactions in COVID− 19 lungs is
challenging, mainly because of the marked cellular infiltrate and architecturally distorted …

[HTML][HTML] Mechanisms of neutrophil extracellular trap in chronic inflammation of endothelium in atherosclerosis

X Yang, Y Ma, X Chen, J Zhu, W Xue, K Ning - Life Sciences, 2023 - Elsevier
Cardiovascular diseases are a primary cause of morbidity and mortality around the world. In
addition, atherosclerosis (AS)-caused cardiovascular disease is the primary cause of death …

Heparin, low molecular weight heparin, and non-anticoagulant derivatives for the treatment of inflammatory lung disease

JK Shute - Pharmaceuticals, 2023 - mdpi.com
Unfractionated heparin has multiple pharmacological activities beyond anticoagulation.
These anti-inflammatory, anti-microbial, and mucoactive activities are shared in part by low …

Neutrophil extracellular traps in tumor progression and immunotherapy

M Yan, Y Gu, H Sun, Q Ge - Frontiers in Immunology, 2023 - frontiersin.org
Tumor immunity is a growing field of research that involves immune cells within the tumor
microenvironment. Neutrophil extracellular traps (NETs) are neutrophil-derived extracellular …

Fluorometric quantification of total cell-free DNA as a prognostic biomarker in non-small-cell lung cancer patients treated with immune checkpoint blockade

J Oliver, JL Onieva, M Garrido-Barros, M Cobo-Dols… - Cancers, 2023 - mdpi.com
Simple Summary The current study investigated the potential use of fluorometric cfDNA
quantification as a prognostic biomarker in advanced non-small cell lung cancer (NSCLC) …

SIgA in various pulmonary diseases

X Wang, J Zhang, Y Wu, Y Xu, J Zheng - European Journal of Medical …, 2023 - Springer
Secretory immunoglobulin A (SIgA) is one of the most abundant immunoglobulin subtypes
among mucosa, which plays an indispensable role in the first-line protection against …

Involucrasin B suppresses airway inflammation in obese asthma by inhibiting the TLR4-NF-κB-NLRP3 pathway

Z Yang, X Li, L Wei, L Bao, H Hu, L Liu, W Tan, X Tong… - Phytomedicine, 2024 - Elsevier
Background Obese asthma is an asthma phenotype that causes more severe lung
inflammation and airway hyperresponsiveness than allergic asthma and it is resistant to …

Circulating interleukin-8 dynamics parallels disease course and is linked to clinical outcomes in severe COVID-19

R D'Rozario, D Raychaudhuri, P Bandopadhyay… - Viruses, 2023 - mdpi.com
Severe COVID-19 frequently features a systemic deluge of cytokines. Circulating cytokines
that can stratify risks are useful for more effective triage and management. Here, we ran a …