Tools and techniques for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/COVID-19 detection

SH Safiabadi Tali, JJ LeBlanc, Z Sadiq… - Clinical microbiology …, 2021 - Am Soc Microbiol
SUMMARY The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and …

Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses—are we our own worst enemy?

LYR Wong, S Perlman - Nature Reviews Immunology, 2022 - nature.com
Human coronaviruses cause a wide spectrum of disease, ranging from mild common colds
to acute respiratory distress syndrome and death. Three highly pathogenic human …

Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19

MC Woodruff, RP Ramonell, DC Nguyen… - Nature …, 2020 - nature.com
A wide spectrum of clinical manifestations has become a hallmark of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) COVID-19 pandemic, although the …

The SARS-CoV-2 nucleocapsid protein and its role in viral structure, biological functions, and a potential target for drug or vaccine mitigation

Z Bai, Y Cao, W Liu, J Li - Viruses, 2021 - mdpi.com
The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the world
is still expanding. Thus, there is an urgent need to better understand this novel virus and find …

Antibody tests for identification of current and past infection with SARS‐CoV‐2

T Fox, J Geppert, J Dinnes, K Scandrett… - Cochrane database …, 2022 - cochranelibrary.com
Background The diagnostic challenges associated with the COVID‐19 pandemic resulted in
rapid development of diagnostic test methods for detecting SARS‐CoV‐2 infection. Serology …

Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

MJ Carter, M Fish, A Jennings, KJ Doores, P Wellman… - Nature medicine, 2020 - nature.com
Recent reports highlight a new clinical syndrome in children related to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)—multisystem inflammatory syndrome in …

Antibody response to SARS-CoV-2 infection in humans: A systematic review

N Post, D Eddy, C Huntley, MCI Van Schalkwyk… - PloS one, 2020 - journals.plos.org
Background Progress in characterising the humoral immune response to Severe Acute
Respiratory Syndrome 2 (SARS-CoV-2) has been rapid but areas of uncertainty persist …

Detection of COVID-19: A review of the current literature and future perspectives

T Ji, Z Liu, GQ Wang, X Guo, C Lai, H Chen… - Biosensors and …, 2020 - Elsevier
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to the coronavirus disease 2019 (COVID-19) worldwide pandemic. This unprecedented …

Dynamic changes in anti-SARS-CoV-2 antibodies during SARS-CoV-2 infection and recovery from COVID-19

K Li, B Huang, M Wu, A Zhong, L Li, Y Cai… - Nature …, 2020 - nature.com
Deciphering the dynamic changes in antibodies against SARS-CoV-2 is essential for
understanding the immune response in COVID-19 patients. Here we analyze the laboratory …

Viral dynamics and real-time RT-PCR Ct values correlation with disease severity in COVID-19

AA Rabaan, R Tirupathi, AA Sule, J Aldali, AA Mutair… - Diagnostics, 2021 - mdpi.com
Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease
2019 (COVID-19). However, many scientists disagree, and it is essential to understand that …