Obesity is a complex and heterogeneous condition that leads to various metabolic
complications, including type 2 diabetes. Unfortunately, for some, treatment options to date …

Across the lifespan, the human body and brain endure the impact of a plethora of
exogenous and endogenous factors that determine the health outcome in old age. The …

Background: Obesity and hidradenitis suppurativa (HS) are related through meta-
inflammation and are both associated with increased cardiometabolic risk. Notwithstanding …

The diagnosis of metabolic syndrome is based on the presence of central (abdominal)
obesity, increased blood pressure, elevated glucose and triglycerides, and low high-density …

A fatty liver index (FLI) greater than sixty (FLI≥ 60) is an established score for metabolic
dysfunction-associated steatotic liver disease (MASLD), which carries a high risk for …

Background Prediabetes, an intermediate stage between normal blood sugar levels and a
diabetes mellitus diagnosis, is increasing in prevalence. Severe prediabetes is associated …

To the Editor: By 2050, more than 1.3 billion people worldwide are expected to have
diabetes, with the vast majority having type 2 diabetes [1]. Type 2 diabetes is associated with …

However, systemic delivery of small-molecular trigger compounds faces pharmacokinetic
challenges and can cause side-effects, and traceless triggers, such as light, ultrasound …

Studies have reported inconsistent results about the risk of incident chronic kidney disease
(CKD) in people with metabolically healthy obesity (MHO). We designed this systematic …

ABSTRACT Introduction Sarcopenic obesity (SarcO) is defined as the confluence of reduced
muscle mass and function and excess body fat. The scientific community is increasingly …