Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?

M Leaver, D Wells - Human reproduction update, 2020 - academic.oup.com
BACKGROUND Preimplantation genetic testing (PGT) encompasses methods that allow
embryos to be tested for severe inherited conditions or for chromosome abnormalities …

[HTML][HTML] Recent advances in treatment of recurrent spontaneous abortion

T Deng, X Liao, S Zhu - Obstetrical & gynecological survey, 2022 - journals.lww.com
Recent Advances in Treatment of Recurrent Spontaneous Aborti... : Obstetrical & Gynecological
Survey Recent Advances in Treatment of Recurrent Spontaneous Abortion : Obstetrical & …

[HTML][HTML] A non-invasive artificial intelligence approach for the prediction of human blastocyst ploidy: a retrospective model development and validation study

J Barnes, M Brendel, VR Gao, S Rajendran… - The Lancet Digital …, 2023 - thelancet.com
Background One challenge in the field of in-vitro fertilisation is the selection of the most
viable embryos for transfer. Morphological quality assessment and morphokinetic analysis …

Good practice recommendations on add-ons in reproductive medicine

ESHRE Add-ons working group, K Lundin… - Human …, 2023 - academic.oup.com
STUDY QUESTION Which add-ons are safe and effective to be used in ART treatment?
SUMMARY ANSWER Forty-two recommendations were formulated on the use of add-ons in …

Multicenter prospective study of concordance between embryonic cell-free DNA and trophectoderm biopsies from 1301 human blastocysts

C Rubio, L Navarro-Sánchez… - American journal of …, 2020 - Elsevier
Background The recent identification of embryonic cell-free DNA in spent blastocyst media
has opened a new era of possibilities for noninvasive embryo aneuploidy testing in assisted …

[HTML][HTML] Preimplantation genetic testing for chromosomal abnormalities: aneuploidy, mosaicism, and structural rearrangements

M Viotti - Genes, 2020 - mdpi.com
There is a high incidence of chromosomal abnormalities in early human embryos, whether
they are generated by natural conception or by assisted reproductive technologies (ART) …

Embryo Ranking Intelligent Classification Algorithm (ERICA): artificial intelligence clinical assistant predicting embryo ploidy and implantation

A Chavez-Badiola, A Flores-Saiffe-Farías… - Reproductive …, 2020 - Elsevier
Research question Can a deep machine learning artificial intelligence algorithm predict
ploidy and implantation in a known data set of static blastocyst images, and how does its …

[HTML][HTML] Preimplantation genetic testing for aneuploidy–a castle built on sand

N Gleicher, P Patrizio, A Brivanlou - Trends in molecular medicine, 2021 - cell.com
Preimplantation genetic testing for aneuploidy (PGT-A) has become a routine add-on for in
vitro fertilization (IVF) to determine whether human embryos are to be clinically utilized or …

Liquid Biopsy Based on Cell-Free DNA and RNA

C Loy, L Ahmann, I De Vlaminck… - Annual Review of …, 2024 - annualreviews.org
This review delves into the rapidly evolving landscape of liquid biopsy technologies based
on cell-free DNA (cfDNA) and cell-free RNA (cfRNA) and their increasingly prominent role in …

[HTML][HTML] The future of IVF: the new normal in human reproduction

VA Kushnir, GD Smith, EY Adashi - Reproductive Sciences, 2022 - Springer
Increased demand for in vitro fertilization (IVF) due to socio-demographic trends, and supply
facilitated by new technologies, converged to transform the way a substantial proportion of …