Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …

Objective While endothelial dysfunction has been implicated in the widespread
thromboinflammatory complications of COVID‐19, the upstream mediators of …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently causing a
global pandemic. The antigen specificity of the antibody response mounted against this …

Abstract Development of antibody protection during SARS-CoV-2 infection is a pressing
question for public health and for vaccine development. We developed highly sensitive …

Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

The release of neutrophil extracellular traps (NETs) by hyperactive neutrophils is recognized
to play an important role in the thromboinflammatory milieu inherent to severe presentations …

A subset of patients with coronavirus disease 2019 (COVID-19) become critically ill,
suffering from severe respiratory problems and also increased rates of thrombosis. The …

Down's syndrome (DS) presents with a constellation of cardiac, neurocognitive and growth
impairments. Individuals with DS are also prone to severe infections and autoimmunity …

Over the past year, the SARS-CoV-2 pandemic has swept the globe, resulting in an
enormous worldwide burden of infection and mortality. However, the additional toll resulting …

Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has
resulted in over 450 million cases with more than 6 million deaths worldwide, causing global …