Instructing durable humoral immunity for COVID-19 and other vaccinable diseases

D Bhattacharya - Immunity, 2022 - cell.com
Many aspects of SARS-CoV-2 have fully conformed with the principles established by
decades of viral immunology research, ultimately leading to the crowning achievement of …

[PDF][PDF] Distinctive features of SARS-CoV-2-specific T cells predict recovery from severe COVID-19

J Neidleman, X Luo, AF George, M McGregor, J Yang… - Cell Reports, 2021 - cell.com
Although T cells are likely players in severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) immunity, little is known about the phenotypic features of SARS-CoV-2 …

[HTML][HTML] Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice

E Ricker, M Manni, D Flores-Castro, D Jenkins… - Nature …, 2021 - nature.com
Differences in immune responses to viruses and autoimmune diseases such as systemic
lupus erythematosus (SLE) can show sexual dimorphism. Age-associated B cells (ABC) are …

[HTML][HTML] Duration of post–COVID-19 symptoms is associated with sustained SARS-CoV-2–specific immune responses

JK Files, S Sarkar, TR Fram, S Boppana, S Sterrett… - JCI insight, 2021 - ncbi.nlm.nih.gov
A subset of COVID-19 patients exhibit post-acute sequelae of COVID-19 (PASC), but little is
known about the immune signatures associated with these syndromes. We investigated …

[HTML][HTML] The molecular mechanism of SARS-CoV-2 evading host antiviral innate immunity

W Gu, H Gan, Y Ma, L Xu, ZJ Cheng, B Li, X Zhang… - Virology journal, 2022 - Springer
Abstract The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has resulted in a global health emergency (COVID-19) because of its rapid spread …

[HTML][HTML] Long COVID in autoimmune rheumatic diseases

Y Fedorchenko, O Zimba - Rheumatology International, 2023 - Springer
Abstract Consequences of Corona Virus Disease-19 (COVID-19) in patients with rheumatic
diseases (RDs) are clinically diverse. SARS-CoV-2 infection has been associated with …

[HTML][HTML] Influence of obesity on serum levels of SARS-CoV-2-specific antibodies in COVID-19 patients

D Frasca, L Reidy, C Cray, A Diaz, M Romero, K Kahl… - PLoS …, 2021 - journals.plos.org
SARS-CoV-2 (Severe Acute Respiratory Syndrome Corona Virus-2), cause of COVID-19
(Coronavirus Disease of 2019), represents a significant risk to people living with pre-existing …

Molecular mechanisms controlling age‐associated B cells in autoimmunity

S Phalke, J Rivera‐Correa, D Jenkins… - Immunological …, 2022 - Wiley Online Library
Age‐associated B cells (ABCs) have emerged as critical components of immune responses.
Their inappropriate expansion and differentiation have increasingly been linked to the …

[HTML][HTML] The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing

D Frasca, L Reidy, M Romero, A Diaz, C Cray… - International Journal of …, 2022 - nature.com
Background/objectives Obesity decreases the secretion of SARS-CoV-2-specific IgG
antibodies in the blood of COVID-19 patients. How obesity impacts the quality of the …

Immune imprinting and next-generation coronavirus vaccines

CQ Huang, S Vishwanath, GW Carnell, ACY Chan… - Nature …, 2023 - nature.com
Vaccines based on historical virus isolates provide limited protection from continuously
evolving RNA viruses, such as influenza viruses or coronaviruses, which occasionally spill …