To this date, over 100 different types of RNA modification have been identified. Methylation
of different RNA species has emerged as a critical regulator of transcript expression. RNA …

Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

Abstract Background N6-methyladenosine (m 6 A) modification is an emerging layer of
epigenetic regulation which is widely implicated in the tumorigenicity of hepatocellular …

Liver cancer is a common cancer worldwide. Although the etiological factors of liver
carcinogenesis are well defined, the underlying molecular mechanisms remain largely …

In recent years, the prevalence of obesity and cancer have been rising. Since this poses a
serious threat to human health, the relationship between the two has attracted much …

Emerging evidence has indicated that peroxisome proliferator-activated receptor-gamma
coactivator-1α (PPARGC1A) is involved in hepatocellular carcinoma (HCC). However, its …

The tumor microenvironment (TME), which is regulated by intrinsic oncogenic mechanisms
and epigenetic modifications, has become a research hotspot in recent years. Characteristic …

The development of next-generation sequencing technology and the discovery of specific
antibodies targeting chemically modified nucleotides have paved the way for a new era of …

Aims Hepatocellular carcinoma (HCC), one of the most common cancer, causes the fourth
cancer-related deaths around the world. N6-methyladenosine (m 6 A) has been reported to …

RNA methylation has emerged as a fundamental process in epigenetic regulation.
Accumulating evidences indicate that RNA methylation is essential for many biological …