[HTML][HTML] Pharmacological properties and underlying mechanisms of curcumin and prospects in medicinal potential

YS Fu, TH Chen, L Weng, L Huang, D Lai… - Biomedicine & …, 2021 - Elsevier
Curcumin, isolated from Curcuma longa L., is a fat-soluble natural compound that can be
obtained from ginger plant tuber roots, which accumulative evidences have demonstrated …

The effectiveness of nano‐curcumin on patients with COVID‐19: A systematic review of clinical trials

M Shojaei, S Foshati, M Abdi, G Askari… - Phytotherapy …, 2023 - Wiley Online Library
The main aim of the current study was to summarize the findings of available clinical studies
to assess nano‐curcumin's influence on COVID patients. A comprehensive online search …

Recent advances in codelivery of curcumin and siRNA as anticancer therapeutics

M Sanati, AR Afshari, P Kesharwani… - European Polymer …, 2023 - Elsevier
Addressing the need for effective cancer chemotherapy with low adverse effects has been
partially possible through innovative therapeutic approaches combining chemotherapeutics …

[HTML][HTML] Phytochemicals as modulators of paraoxonase-1 in health and diseases

ZN Arab, D Khayatan, SM Razavi, K Zare… - Antioxidants, 2022 - mdpi.com
Chronic diseases such as cardiovascular disease (CVD), atherosclerosis, chronic liver
disease, and neurodegenerative diseases are major causes of mortality. These diseases …

Lung pneumonitis and fibrosis in cancer therapy: a review on cellular and molecular mechanisms

C Xu, Z Shang, M Najafi - Current Drug Targets, 2022 - ingentaconnect.com
Fibrosis and pneumonitis are the most important side effects of lung tissue following cancer
therapy. Radiotherapy and chemotherapy by some drugs, such as bleomycin, can induce …

Superoxide dismutase: a key target for the neuroprotective effects of curcumin

D Khayatan, SM Razavi, ZN Arab, Y Hosseini… - Molecular and Cellular …, 2024 - Springer
Over the past few years, the prevalence of neurodegenerative diseases (NDD) has
increased dramatically. The community health system is burdened by the high healthcare …

The effect of medicinal plants on cirrhosis: A systematic review of clinical trials

S Amini, M Bagherniya, AE Butler… - Phytotherapy …, 2023 - Wiley Online Library
Medicinal plants with minimal side effects, low cost, and liver‐protective effects can be a
suitable treatment option for cirrhosis. Therefore, this systematic review aimed to determine …

[HTML][HTML] Potential “therapeutic” effects of tocotrienol-rich fraction (TRF) and carotene “against” bleomycin-induced pulmonary fibrosis in rats via TGF-β/Smad, PI3K/Akt …

Y Lu, Y Zhang, Z Pan, C Yang, L Chen, Y Wang, D Xu… - Nutrients, 2022 - mdpi.com
Background: Pulmonary fibrosis (PF) is a chronic, progressive, and, ultimately, terminal
interstitial disease caused by a variety of factors, ranging from genetics, bacterial, and viral …

Colon delivery of resveratrol for the treatment of inflammatory bowel disease

HS Sardou, PR Vosough, M Abbaspour… - Journal of Drug Delivery …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal
tract (GIT) that can affect any part of the GIT. The side effects of chemical drugs in the …

[HTML][HTML] Crocin supplementation in primary open angle glaucoma: A randomized, triple-blind, placebo-controlled clinical trial

S Mahdiani, S Shokoohi-Rad, S Sepahi… - Medicine in Drug …, 2024 - Elsevier
Purpose Glaucoma is the leading cause of irreversible visual loss in the world. The present
study was designed to evaluate the beneficial effects of crocin, as a supplement, in the …