Metabolic contribution to age-related chromosome missegregation in mammalian oocytes

BP Mihalas, AL Marston, LE Wu, RB Gilchrist - Reproduction, 2024 - rep.bioscientifica.com
Advanced maternal age is a major cause of infertility, miscarriage, and congenital
abnormalities. This is principally caused by a decrease in oocyte quality and developmental …

The Impact of Maternal Age on Aneuploidy in Oocytes: Reproductive Consequences, Molecular Mechanisms, and Future Directions

W Huang, X Li, H Yang, H Huang - Ageing Research Reviews, 2024 - Elsevier
Age-related aneuploidy in human oocytes is a major factor contributing to decreased fertility
and adverse reproductive outcomes. As females age, their oocytes are more prone to …

Bacillus licheniformis ameliorates Aflatoxin B1-induced testicular damage by improving the gut-metabolism-testis axis

FL Zhang, HH Ma, PY Dong, YMC Yan, Y Chen… - Journal of Hazardous …, 2024 - Elsevier
Abstract Global aflatoxin B1 (AFB1) contamination is inevitable, and it can significantly
damage testicular development. However, the current mechanism is confusing. Here, by …

3-Methyl-4-nitrophenol Exposure Deteriorates Oocyte Maturation by Inducing Spindle Instability and Mitochondrial Dysfunction

F Chen, AF Luo, MG Li, LX Zheng, H Gu… - International Journal of …, 2024 - mdpi.com
3-methyl-4-nitrophenol (PNMC), a well-known constituent of diesel exhaust particles and
degradation products of insecticide fenitrothion, is a widely distributed environmental …

沉默信息调节因子2 介导蛋白质去乙酰化与卵母细胞衰老.

金清美, 韩乔松, 梁竞男, 周悦… - Journal of …, 2024 - search.ebscohost.com
女性卵巢衰老远比机体其他器官衰老要早. 随着人类生育年龄的推迟, 卵巢衰老导致的不孕症所
占比重越来越大. 卵巢衰老是以卵母细胞的数量和质量下降为特征的一个自然生理过程 …

FROM PATHOPHYSIOLOGY TO POTENTIAL INTERVENTIONS: INVESTIGATING THE INTRICATE DYNAMICS OF POLYCYSTIC OVARY SYNDROME, AGING, AND …

P Kabakchieva - Anti-Aging Eastern Europe, 2023 - antiagingeeu.com
Polycystic ovary syndrome (PCOS) and age-related decline in fertility are complex issues
affecting women's reproductive health. This review aims to explore the intricate dynamics …