Rotational thromboelastometry (ROTEM) is a point-of-care viscoelastic method and enables
to assess viscoelastic profiles of whole blood in various clinical settings. ROTEM-guided …

Viscoelastic hemostatic assay (VHAs) are whole blood point-of-care tests that have become
an essential method for assaying hemostatic competence in liver transplantation, cardiac …

The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

Background Major haemorrhage is a clinical emergency that results in morbidity and
mortality: practice guidance is important to reduce these risks. Delayed recognition of …

Thromboelastography (TEG) and rotational thromboelastometry (ROTEM) are point‐of‐care
viscoelastic devices that use whole blood samples to assess coagulation and fibrinolysis …

Hypercoagulability is an increasingly recognized complication of SARS‐CoV‐2 infection. As
such, anticoagulation has become part and parcel of comprehensive COVID‐19 …

Infection by SARS-CoV-2 is associated with a high risk of thrombosis. The laboratory
documentation of hypercoagulability and impaired fibrinolysis remains a challenge. Our aim …

The transmembrane P-glycoprotein (P-gp) pumps that efflux drugs are a major mechanism
of cancer drug resistance. They are also important in protecting normal tissue cells from …

Essentials• TEG‐guided therapy has been shown to be valuable in a number of surgical
settings.• This systematic review and analysis specifically evaluated the effects of TEG …

Background Reducing operative blood loss improves patient outcomes and reduces
healthcare costs. The aim of this article was to review current surgical, anaesthetic and …