Fetal cholinergic anti-inflammatory pathway and necrotizing enterocolitis: the brain-gut connection begins in utero

L Garzoni, C Faure, MG Frasch - Frontiers in integrative neuroscience, 2013 - frontiersin.org
Necrotizing enterocolitis (NEC) is an acute neonatal inflammatory disease that affects the
intestine and may result in necrosis, systemic sepsis and multisystem organ failure. NEC …

[HTML][HTML] Prenatal inflammation enhances antenatal corticosteroid–induced fetal lung maturation

AF Schmidt, PS Kannan, J Bridges, P Presicce… - JCI insight, 2020 - ncbi.nlm.nih.gov
Respiratory complications are the major cause of morbidity and mortality among preterm
infants, which is partially prevented by the administration of antenatal corticosteroids (ACS) …

Depth of bacterial invasion in resected intestinal tissue predicts mortality in surgical necrotizing enterocolitis

JI Remon, SC Amin, SR Mehendale, R Rao… - Journal of …, 2015 - nature.com
Objective: Up to a third of all infants who develop necrotizing enterocolitis (NEC) require
surgical resection of necrotic bowel. We hypothesized that the histopathological findings in …

Necrotizing enterocolitis is associated with ureaplasma colonization in preterm infants

AC Okogbule-Wonodi, GW Gross, CCJ Sun… - Pediatric …, 2011 - nature.com
The study objective was to determine whether Ureaplasma respiratory tract colonization of
preterm infants< 33 wk gestation is associated with an increased risk for necrotizing …

Impact of fetal inflammatory response on the severity of necrotizing enterocolitis in preterm infants

IN Mir, M Sánchez-Rosado, J Reis, N Uddin… - Pediatric …, 2024 - nature.com
Objective Neonates born with fetal inflammatory response (FIR) are at increased risk for
adverse neonatal outcomes. Our objective was to determine whether FIR and its severity is …

The Mediterranean diet adherence by pregnant women delivering prematurely: association with size at birth and complications of prematurity

E Parlapani, C Agakidis… - The Journal of …, 2019 - Taylor & Francis
Abstract Background The Mediterranean diet (MD) is associated with decreased risk of
metabolic syndrome and gestational diabetes due to the anti-inflammatory and antioxidative …

Moderate postnatal hyperoxia accelerates lung growth and attenuates pulmonary hypertension in infant rats after exposure to intra-amniotic endotoxin

JR Tang, GJ Seedorf, V Muehlethaler… - … of Physiology-Lung …, 2010 - journals.physiology.org
To determine the separate and interactive effects of fetal inflammation and neonatal
hyperoxia on the developing lung, we hypothesized that: 1) antenatal endotoxin (ETX) …

The role of neutrophils in pregnancy, term and preterm labour

B Gimeno-Molina, I Muller, P Kropf, L Sykes - Life, 2022 - mdpi.com
Neutrophils are surveillance cells, and the first to react and migrate to sites of inflammation
and infection following a chemotactic gradient. Neutrophils play a key role in both sterile …

Gut and immune effects of bioactive milk factors in preterm pigs exposed to prenatal inflammation

S Ren, Y Hui, S Goericke-Pesch… - American Journal …, 2019 - journals.physiology.org
Prenatal inflammation may predispose to preterm birth and postnatal inflammatory disorders
such as necrotizing enterocolitis (NEC). Bioactive milk ingredients may help to support gut …

A perfect storm: fetal inflammation and the developing immune system

D Sabic, JM Koenig - Pediatric research, 2020 - nature.com
Histologic chorioamnionitis is an inflammatory disorder of the placenta that commonly
precedes preterm delivery. Preterm birth related to chorioamnionitis and fetal inflammation …