OBJECTIVE:: To examine whether COMT (catechol-O-methyltransferase) polymorphism
modulates aspects of sleep in children diagnosed with attention-deficit/hyperactivity disorder …

Single-chain Fv and single-domain antibodies retain the binding specificity of full-length
antibodies but they can be cloned, selected, engineered, and manipulated as genes. When …

Aims The aim of the study is to evaluate the neuroprotective effects of continuous
dopaminergic stimulation (CDS) by rotigotine-loaded microspheres (RoMS) in a mouse …

In this review, we report how proteomic methodologies have been used to investigate
cellular and animal models of Parkinson's disease (PD), with a special focus on α-synuclein …

The effect of the bis-sulfonated iron (III) corrole (1-Fe), a potent decomposition catalyst of
reactive oxygen species, on rescuing SN4741 cells that were damaged by 6 …

Neurotransmitters such as dopamine play an important role in reproductive behaviors and
signaling. Neuroendocrine-active chemicals in the environment have potential to interfere …

Prolonged treatment of Parkinson's disease (PD) with levodopa leads to disabling side
effects collectively referred to as 'dyskinesias'. We hypothesized that bioenergetic function in …

One of the common features occurring in several experimental models of neurodegenerative
disorders is oxidative/nitrosative stress (OS/NS). This event induces a series of deleterious …

Dopamine‐induced neuronal cytotoxicity has been proposed as a leading pathological
mechanism underlying many neuronal degenerative disorders including Parkinson disease …

Cellular homeostasis relies on quality control systems so that damaged biologic structures
are either repaired or degraded and entirely replaced by newly formed proteins or even …