Frailty is a highly prevalent condition in the elderly that has been increasingly considered as
a crucial public health issue, due to the strict correlation with a higher risk of fragility …

Sarcopenia represents a major health burden in industrialized country by reducing
substantially the quality of life. Indeed, it is characterized by a progressive and generalized …

Osteoporosis is characterized by an alteration of bone microstructure with a decreased bone
mineral density, leading to the incidence of fragility fractures. Around 200 million people are …

In recent years, the interest in oxygen–ozone (O2O3) therapy application has considerably
increased in the field of rehabilitation. Despite its widespread use in common clinical …

Osteoarthritis (OA) is the most well-known degenerative disease among the geriatric and is
a main cause of significant disability in daily living. It has a multifactorial etiology and is …

Osteoarthritis (OA) is a multifactorial joint disease characterized by degeneration of articular
cartilage, which leads to joints pain, disability and reduced quality of life in patients with OA …

Some say that all diseases begin in the gut. Interestingly, this concept is actually quite old,
since it is attributed to the Ancient Greek physician Hippocrates, who proposed the …

Osteoarthritis (OA) is the most common form of arthritis and age-related degenerative joint
disorder, which adversely affects quality of life and causes disability. However, the …

Osteoarthritis (OA) is a painful and disabling disease that affects millions of patients. Its
etiology is largely unknown, but it is most likely multifactorial. OA pathogenesis involves the …

BACKGROUND: There is little evidence on intra-articular (IA) treatment in knee osteoarthritis
(KOA) and there is a lack of long-term follow-up studies. OBJECTIVE: To assess the long …