COVID-19-associated coagulopathy and antithrombotic agents—lessons after 1 year

J Leentjens, TF Van Haaps, PF Wessels… - The Lancet …, 2021 - thelancet.com
COVID-19 is associated with a high incidence of thrombotic complications, which can be
explained by the complex and unique interplay between coronaviruses and endothelial …

Venous thromboembolism in COVID-19 compared to non-COVID-19 cohorts: a systematic review with meta-analysis

A Tufano, D Rendina, V Abate, A Casoria… - Journal of clinical …, 2021 - mdpi.com
Background: A high incidence of venous thromboembolism (VTE) is reported in hospitalized
COVID-19 patients, in particular in patients admitted to the intensive care unit (ICU). In …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
Background REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and
imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV …

[HTML][HTML] Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group - Lancet (London, England), 2022 - ncbi.nlm.nih.gov
Background Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-
thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients …

Platelets amplify endotheliopathy in COVID-19

TJ Barrett, MI Cornwell, K Myndzar, CC Rolling… - Science …, 2021 - science.org
Given the evidence for a hyperactive platelet phenotype in COVID-19, we investigated
effector cell properties of COVID-19 platelets on endothelial cells (ECs). Integration of EC …

Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

O Abani, A Abbas, F Abbas, M Abbas, S Abbasi… - The Lancet, 2022 - thelancet.com
Background Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-
thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients …

COVID-19 critical illness: a data-driven review

JC Ginestra, OJL Mitchell, GL Anesi… - Annual review of …, 2022 - annualreviews.org
The coronavirus disease 2019 (COVID-19) pandemic has posed unprecedented challenges
in critical care medicine, including extreme demand for intensive care unit (ICU) resources …

Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

PW Horby, G Pessoa-Amorim, N Staplin… - The …, 2021 - orca.cardiff.ac.uk
Background Aspirin has been proposed as a treatment for COVID-19 on the basis of its anti-
thrombotic properties. We aimed to evaluate the efficacy and safety of aspirin in patients …

The immune response as a double‐edged sword: The lesson learnt during the COVID‐19 pandemic

C Agrati, R Carsetti, V Bordoni, A Sacchi… - …, 2022 - Wiley Online Library
The COVID‐19 pandemic has represented an unprecedented challenge for the humanity,
and scientists around the world provided a huge effort to elucidate critical aspects in the fight …

From co-infections to autoimmune disease via hyperactivated innate immunity: COVID-19 autoimmune coagulopathies, autoimmune myocarditis and multisystem …

R Root-Bernstein - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophilia and the production of neutrophil extracellular traps (NETs) are two of many
measures of increased inflammation in severe COVID-19 that also accompany its …