Pseudomonas aeruginosa, an increasingly common competitive and biofilm organism in
healthcare infection with sophisticated, interlinked and hierarchic quorum systems (Las, Rhl …

The tremendous increase in the bacterial resistance to the available antibiotics is a serious
problem for the treatment of various infections. Biofilm formation in bacteria significantly …

Biofilm is a community of microorganisms attached to the substrate and plays a significant
role in microbial pathogenesis and medical device-related infection. Pseudomonas …

In the present study, norlobaridone (NBD) was isolated from Parmotrema and then
evaluated as a new potent quorum sensing (QS) inhibitor against Pseudomonas aeruginosa …

The search for new classes of antibiotics is a real concern of public health due to the
emergence of multi-resistant bacteria strains. We report herein the synthesis and …

The development of bacterial resistance to chemical therapy poses a severe danger to
efficacy of treating bacterial infections. One of the key factors for resistance to antimicrobial …

In the present study, we characterized Bakuchiol (Bak) as a new potent quorum sensing
(QS) inhibitor against Pseudomonas aeruginosa biofilm formation. Upon extensive in vitro …

Pseudomonas aeruginosa is a widespread γ-proteobacterium and an important
opportunistic pathogen. The genetically diverse P. aeruginosa phylogroup 3 strains are …

The biofilm formation is still prevalent mechanism of developing the drug resistance in the
Pseudomonas aeruginosa, gram-negative bacteria, known for its major role in nosocomial …

Methods: In silico identification of potential LasR or NOR inhibitors was attempted through a
virtual screening platform AtomNet® to obtain a final subset of< 100 top scoring compounds …