Different species of the ascomycetous yeastlike fungus Pneumocystis asymptomatically
infect/colonize numerous healthy mammalian hosts and in immune-compromised mammals …

Cytomegalovirus (CMV) infection is associated with Pneumocystis jirovecii pneumonia (PJP)
in kidney transplant recipients (KTRs), but its impact on clinical severity and outcomes in …

Introduction There was a growing need for practical guidelines for the most common OIs in
Germany and Austria under consideration of the local epidemiological conditions. Materials …

Although combination therapy using trimethoprim–sulfamethoxazole (TMP–SMX) plus
echinocandins has been reported to reduce the mortality of patients with pneumocystis …

Objectives To investigate short-term prognosis and prognostic factors for connective tissue
disease-associated pneumocystis pneumonia (CTD-PCP) using the Japanese nationwide …

Pulmonary diseases are major causes of morbidity and death in persons with HIV infection.
Millions of people with HIV/AIDS throughout the world are at risk of opportunistic …

Objectives The aim of this study was to investigate the efficacy of combination therapy of
caspofungin and TMP/SMZ (trimethoprim/sulfamethoxazole) in moderate to severe …

Objectives The effectiveness of trimethoprim/sulfamethoxazole (TMP/SMZ) for pneumocystis
pneumonia (PCP) is limited with adverse events. Caspofungin, by inhibiting the cyst form of …

Background Opportunistic infection has been documented in systemic lupus erythematosus
with special attention paid to Pneumocystis jirovecii because of the significant morbidity and …

Quinone reductase 2 (NQO2) is an FAD-linked enzyme and the only known human target of
two antimalarial drugs, primaquine (PQ) and chloroquine (CQ). The structural differences …