The origin and mechanisms of smooth muscle cell development in vertebrates

M Donadon, MM Santoro - Development, 2021 - journals.biologists.com
Smooth muscle cells (SMCs) represent a major structural and functional component of many
organs during embryonic development and adulthood. These cells are a crucial component …

iPSCs-based generation of vascular cells: reprogramming approaches and applications

D Klein - Cellular and Molecular Life Sciences, 2018 - Springer
Recent advances in the field of induced pluripotent stem cells (iPSCs) research have
opened a new avenue for stem cell-based generation of vascular cells. Based on their …

Integrating oculomics with genomics reveals imaging biomarkers for preventive and personalized prediction of arterial aneurysms

Y Huang, C Li, D Shi, H Wang, X Shang, W Wang… - EPMA Journal, 2023 - Springer
Objective Arterial aneurysms are life-threatening but usually asymptomatic before requiring
hospitalization. Oculomics of retinal vascular features (RVFs) extracted from retinal fundus …

Role of vascular smooth muscle cell phenotype switching in arteriogenesis

JV Ashraf, A Al Haj Zen - International journal of molecular sciences, 2021 - mdpi.com
Arteriogenesis is one of the primary physiological means by which the circulatory collateral
system restores blood flow after significant arterial occlusion in peripheral arterial disease …

Vascular stem/progenitor cells in vessel injury and repair

J Tao, X Cao, B Yu, A Qu - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Vascular repair upon vessel injury is essential for the maintenance of arterial homeostasis
and function. Stem/progenitor cells were demonstrated to play a crucial role in regeneration …

Distinct cellular mechanisms underlie smooth muscle turnover in vascular development and repair

U Roostalu, B Aldeiri, A Albertini, N Humphreys… - Circulation …, 2018 - Am Heart Assoc
Rationale: Vascular smooth muscle turnover has important implications for blood vessel
repair and for the development of cardiovascular diseases, yet lack of specific transgenic …

Cilia control vascular mural cell recruitment in vertebrates

X Chen, D Gays, C Milia, MM Santoro - Cell reports, 2017 - cell.com
Vascular mural cells (vMCs) are essential components of the vertebrate vascular system,
controlling blood vessel maturation and homeostasis. Discrete molecular mechanisms have …

Migrasome and tetraspanins in vascular homeostasis: concept, present, and future

Y Zhang, J Wang, Y Ding, J Zhang, Y Xu… - Frontiers in Cell and …, 2020 - frontiersin.org
Cell migration plays a critical role in vascular homeostasis. Under noxious stimuli,
endothelial cells (ECs) migration always contributes to vascular repair, while enhanced …

MicroRNA-22 regulates smooth muscle cell differentiation from stem cells by targeting methyl CpG–binding protein 2

H Zhao, G Wen, Y Huang, X Yu, Q Chen… - … , and vascular biology, 2015 - Am Heart Assoc
Objective—In this study, we attempted to uncover the functional impact of microRNA-22 (miR-
22) and its target gene in smooth muscle cell (SMC) differentiation and delineate the …

Roles and functions of antisense lncRNA in vascular aging

XY Cui, JK Zhan, YS Liu - Ageing research reviews, 2021 - Elsevier
Vascular aging is a major cause of morbidity and mortality in the elderly population.
Endothelial cells (ECs) and vascular smooth muscle cells (VSMCs), forming the intima and …