Aortic smooth muscle TRPV4 channels regulate vasoconstriction in high salt-induced hypertension

X Wen, Y Peng, Y Peng, Y Zhu, F Yu, L Geng… - Hypertension …, 2023 - nature.com
Recent studies have focused on the contribution of vascular endothelial transient receptor
potential vanilloid 4 (TRPV4) channels to hypertension. However, in hypertension, TRPV4 …

Nrf-2 signaling inhibits intracranial aneurysm formation and progression by modulating vascular smooth muscle cell phenotype and function

Y Shi, S Li, Y Song, P Liu, Z Yang, Y Liu… - Journal of …, 2019 - Springer
Background Oxidative stress and vascular smooth muscle cell (VSMC) phenotypic
modulation influence intracranial aneurysm (IA) formation and progression. Oxidative stress …

LncRNA UCA1 sponges miR-26a to regulate the migration and proliferation of vascular smooth muscle cells

S Tian, Y Yuan, Z Li, M Gao, Y Lu, H Gao - Gene, 2018 - Elsevier
Background Recent studies have shown that the long non-coding RNA urothelial carcinoma-
associated (UCA1) plays a key role in cardiovascular injury. However, the potential …

Silk fibroin-based bioengineered scaffold for enabling hemostasis and skin regeneration of critical-size full-thickness heat-induced burn wounds

R Ramakrishnan, D Chouhan… - ACS Biomaterials …, 2022 - ACS Publications
Millions of people around the globe are affected by full-thickness skin injuries. A delay in the
healing of such injuries can lead to the formation of chronic wounds, posing several clinical …

Bacterial nanocellulose hydrogel: a promising alternative material for the fabrication of engineered vascular grafts

D Liu, Q Meng, J Hu - Polymers, 2023 - mdpi.com
Blood vessels are crucial in the human body, providing essential nutrients to all tissues
while facilitating waste removal. As the incidence of cardiovascular disease rises, the …

[HTML][HTML] Iron corroded granules inhibiting vascular smooth muscle cell proliferation

D Qiu, Y Deng, Y Wen, J Yin, J Feng, J Huang… - Materials Today Bio, 2022 - Elsevier
In-stent restenosis after interventional therapy remains a severe clinical complication.
Current evidence indicates that neointimal hyperplasia induced by vascular smooth muscle …

Evaluation of a simple off-the-shelf bi-layered vascular scaffold based on poly (L-lactide-co-ε-caprolactone)/silk fibroin in vitro and in vivo

D Jin, J Hu, D Xia, A Liu, H Kuang, J Du… - International Journal of …, 2019 - Taylor & Francis
Purpose: In the field of small-caliber vascular scaffold research, excellent vascular
remodeling is the key to ensuring anticoagulant function. We prepared an off-the-shelf bi …

The involvement of smooth muscle, striated muscle, and the myocardium in Scleroderma: a review

I Bratoiu, AM Burlui, A Cardoneanu… - International Journal of …, 2022 - mdpi.com
Systemic sclerosis (SSc) is a complex autoimmune disease characterized by heterogeneous
changes involving numerous organs and systems. The currently available data indicate that …

Receptor tyrosine kinase: still an interesting target to inhibit the proliferation of vascular smooth muscle cells

Y Xiong, Y Wang, T Yang, Y Luo, S Xu, L Li - American Journal of …, 2023 - Springer
Vascular smooth muscle cells (VSMCs) proliferation is a critical event that contributes to the
pathogenesis of vascular remodeling such as hypertension, restenosis, and pulmonary …

Smooth muscle heterogeneity and plasticity in health and aortic aneurysmal disease

Y Hu, Z Cai, B He - International Journal of Molecular Sciences, 2023 - mdpi.com
Vascular smooth muscle cells (VSMCs) are the predominant cell type in the medial layer of
the aorta, which plays a critical role in the maintenance of aortic wall integrity. VSMCs have …