[HTML][HTML] Distinct patterns of responses in endothelial cells and smooth muscle cells following vascular injury

X Ding, Q An, W Zhao, Y Song, X Tang, J Wang… - JCI insight, 2022 - ncbi.nlm.nih.gov
Vascular smooth muscle cells (SMCs) are heterogeneous, and their differential responses to
vascular injury are not well understood. To address this question, we performed single-cell …

Development of molecular therapies for venous malformations

J Kangas, M Nätynki, L Eklund - Basic & Clinical Pharmacology …, 2018 - Wiley Online Library
Vascular anomalies are localized defects of morphogenesis that can affect lymphatic and
blood vessels. They are generally called birthmarks, typically observed soon after birth and …

Vascular stem/progenitor cell migration and differentiation in atherosclerosis

B Yu, Q Chen, A Le Bras, L Zhang… - Antioxidants & redox …, 2018 - liebertpub.com
Significance: Atherosclerosis is a major cause for the death of human beings, and it takes
place in large-and middle-sized arteries. The pathogenesis of the disease has been widely …

The role of long non-coding RNA in abdominal aortic aneurysm

Y Xu, S Yang, G Xue - Frontiers in Genetics, 2023 - frontiersin.org
The abdominal aortic aneurysm (AAA) is characterized by segmental expansion of the
abdominal aorta and a high mortality rate. The characteristics of AAA suggest that apoptosis …

The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease

S Hu, A Mahadevan, IF Elysee, J Choi, NR Souchet… - Cell reports, 2021 - cell.com
Intestinal lacteals are essential lymphatic channels for absorption and transport of dietary
lipids and drive the pathogenesis of debilitating metabolic diseases. However, organ …

Extreme diversity of the human vascular mesenchymal cell landscape

LE Bruijn, BEWM van den Akker… - Journal of the …, 2020 - Am Heart Assoc
Background Human mesenchymal cells are culprit factors in vascular (patho) physiology
and are hallmarked by phenotypic and functional heterogeneity. At present, they are …

MiR-149-5p: an Important miRNA regulated by competing endogenous RNAs in diverse human cancers

F Ren, Y Yao, X Cai, Y Cai, Q Su, G Fang - Frontiers in Oncology, 2021 - frontiersin.org
MicroRNAs (miRNAs) consist of a large family of small, non-coding RNAs with the ability to
result in gene silencing post-transcriptionally. With recent advances in research technology …

[HTML][HTML] Atherosclerosis-associated differentially methylated regions can reflect the disease phenotype and are often at enhancers

M Lacey, C Baribault, KC Ehrlich, M Ehrlich - Atherosclerosis, 2019 - Elsevier
Background and aims Atherosclerosis is a widespread and complicated disease involving
phenotypic modulation and transdifferentiation of vascular smooth muscle cells (SMCs), the …

Biocompatible superhydrophobic surface on Zr-based bulk metallic glass: Fabrication, characterization, and biocompatibility investigations

M Zhang, Y Wang, G Ding, R Zheng, R Wei… - Ceramics …, 2023 - Elsevier
Superhydrophobic metal materials are promising candidates for preparing the precision
blood-contacting medical devices. Finding a metal material with excellent biocompatibility …

[HTML][HTML] Impaired vascular smooth muscle cell force-generating capacity and phenotypic deregulation in Marfan Syndrome mice

P Nolasco, CG Fernandes, JC Ribeiro-Silva… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Mechanisms whereby fibrillin-1 mutations determine thoracic aorta aneurysms/dissections
(TAAD) in Marfan Syndrome (MFS) are unclear. Most aortic aneurysms evolve from …