Liraglutide inhibits endothelial-to-mesenchymal transition and attenuates neointima formation after endovascular injury in streptozotocin-induced diabetic mice

TH Tsai, CH Lee, CI Cheng, YN Fang, SY Chung… - Cells, 2019 - mdpi.com
Hyperglycaemia causes endothelial dysfunction, which is the initial process in the
development of diabetic vascular complications. Upon injury, endothelial cells undergo an …

The role of vitamin D in modulating mesenchymal stem cells and endothelial progenitor cells for vascular calcification

YC Hou, CL Lu, CM Zheng, WC Liu, TH Yen… - International Journal of …, 2020 - mdpi.com
Vascular calcification, which involves the deposition of calcifying particles within the arterial
wall, is mediated by atherosclerosis, vascular smooth muscle cell osteoblastic changes …

Non-genomic effect of estradiol on the neurovascular unit and possible involvement in the cerebral vascular accident

FJ Gonçalves, F Abrantes-Soares, MR Pouso… - Molecular …, 2023 - Springer
Cerebrovascular diseases, such as ischemic cerebral vascular accident (CVA), are
responsible for causing high rates of morbidity, mortality, and disability in the population …

Engagement of the CXCL12–CXCR4 Axis in the interaction of endothelial progenitor cell and smooth muscle cell to promote phenotype control and Guard vascular …

SF Mause, E Ritzel, A Deck, F Vogt… - International Journal of …, 2022 - mdpi.com
Endothelial progenitor cells (EPCs) are involved in vascular repair and modulate properties
of smooth muscle cells (SMCs) relevant for their contribution to neointima formation …

LncRNA H19 regulates proliferation, apoptosis and ECM degradation of aortic smooth muscle cells via miR-1-3p/ADAM10 axis in thoracic aortic aneurysm

Z Fan, S Liu, H Zhou - Biochemical Genetics, 2022 - Springer
Thoracic aortic aneurysm (TAA) is a prevalent health problem worldwide. Long non-coding
RNA H19was highly expressed in TAA patients, but the function and mechanism of H19 in …

The transition of smooth muscle cells from a contractile to a migratory, phagocytic phenotype: direct demonstration of phenotypic modulation

ME Sandison, J Dempster… - The Journal of …, 2016 - Wiley Online Library
Key points Smooth muscle cell (SMC) phenotypic conversion from a contractile to a
migratory phenotype is proposed to underlie cardiovascular disease but its contribution to …

Targeting VCAM-1: a therapeutic opportunity for vascular damage

MF Troncoso, MC Díaz-Vesga… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The vascular cell adhesion molecule (VCAM-1) is a transmembrane
sialoglycoprotein detected in activated endothelial and vascular smooth muscle cells …

[HTML][HTML] Kindlin-2 deficiency induces fatal intestinal obstruction in mice

X He, J Song, Z Cai, X Chi, Z Wang, D Yang, S Xie… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Smooth muscle-motility disorders are mainly characterized by impaired
contractility and functional intestinal obstruction. Some of these cases are caused by genetic …

Modulating smooth muscle cell response by the release of TGFβ2 from tubular scaffolds for vascular tissue engineering

DC Ardila, E Tamimi, T Doetschman… - Journal of Controlled …, 2019 - Elsevier
Tissue engineering has gained considerable attention in the development of small diameter
tissue engineered vascular grafts (TEVGs) for treating coronary heart disease. A properly …

Endothelial/epithelial mesenchymal transition in ascending aortas of patients with bicuspid aortic valve

S Maleki, FA Poujade, O Bergman, JR Gådin… - Frontiers in …, 2019 - frontiersin.org
Thoracic aortic aneurysm (TAA) is the progressive enlargement of the aorta due to
destructive changes in the connective tissue of the aortic wall. Aneurysm development is …