Malignant tumors are always a critical threat to human health, with complex pathogenesis,
numerous causative factors, and poor prognosis. The features of cancers, such as gene …

Endothelial dysfunction is widely implicated in cardiovascular pathological changes and
development of vascular disease. In view of the fact that the spontaneous endothelial cell …

To adapt to the plateau environment, Tibetan pigs' lungs have developed a unique
physiological mechanism during evolution. The vascular corrosion casting technique and …

Of the qualities small caliber artificial vascular scaffolds must possess for application in
modified Blalock-Taussig (BT) surgery, effective anticoagulation and mechanical …

Somites are transitory metameric structures at the basis of the axial organization of
vertebrate musculoskeletal system. During evolution, somites appear in the chordate phylum …

Aortic aneurysm (AA), a potentially lethal condition with the characteristic of aortic dilatation,
can only be treated by surgical or endovascular procedures. The underlying mechanisms of …

Cardiovascular diseases cause considerable health and economic burden, as they are the
leading cause of disability and death in the western world. Inactivity, hypertension, obesity …

Smooth muscle alpha-actin (SMA) is a marker for the contractile, non-proliferative phenotype
of adult smooth muscle cells (SMCs). Upon arterial injury, expression of SMA and other …

It has been proposed that smooth muscle differentiation may physically sculpt airway
epithelial branches in mammalian lungs. Serum response factor (SRF) acts with its co-factor …

The objective of this study is to explore the role of the SDF-1α/CXCR4 pathway in the
development of intracranial aneurysm (IA) induced by hemodynamic forces. We collected 12 …