Cardiovascular disease is cited as the underlying cause of death in one out of every three
deaths within the United States; this burden on the health care system percolates down to …

Atherosclerosis results from the excessive accumulation of lipids within the arterial wall.
Lipophagy, referred to as the autophagic degradation of lipids, is a critical mechanism that …

Cardiovascular disease is a globally prevalent disease with far-reaching medical and socio-
economic consequences. Although improvements in treatment pathways and …

Vascular progenitor cells are activated to repair and form a neointima following vascular
damage such as hypertension, atherosclerosis, diabetes, trauma, hypoxia, primary …

Background Smooth muscle cells (SMCs) are the main driver of neointima formation and
restenosis following vascular injury. In animal models, endothelial progenitor cells (EPCs) …

Phenotypic change of vascular smooth muscle cells (VSMCs) is the main contributor of
vascular pathological remodeling in atherosclerosis. The endoplasmic reticulum (ER) is …

Background. Interleukin‐(IL‐) 18 is a proinflammatory cytokine related to cardiovascular
diseases, including hypertension and atherosclerosis. This study is aimed at determining …

Objective: The dysfunction of vascular smooth muscle cells (VSMCs) has been revealed to
be closely linked with the pathogenesis of cardiovascular diseases in diabetes. Recently …

Background: The combination of cardiomyocyte (CM) and vascular cell (VC) fetal
reprogramming upon stress culminates in end-stage heart failure (HF) by mechanisms that …

Contractile to synthetic phenotypic switching of smooth muscle cells (SMCs) contributes to
stenosis in vascular disease and vascular transplants. To generate more contractile SMCs …