HIV and COVID-19: review of clinical course and outcomes

LK Barbera, KF Kamis, SE Rowan… - HIV research & …, 2021 - Taylor & Francis
Background: Understanding the relationship between HIV and SARS-CoV-2 has important
public health implications. Objective: To summarize current research on COVID-19 among …

Effectiveness of Drug Repurposing and Natural Products Against SARS-CoV-2: A Comprehensive Review

PA Velásquez, JC Hernandez, E Galeano… - Clinical …, 2024 - Taylor & Francis
Abstract The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a
betacoronavirus responsible for the COVID-19 pandemic, causing respiratory disorders, and …

[HTML][HTML] Predictors of the prolonged recovery period in COVID-19 patients: a cross-sectional study

SA SeyedAlinaghi, L Abbasian, M Solduzian… - European Journal of …, 2021 - Springer
Background The clinical course of COVID-19 may vary significantly. The presence of
comorbidities prolongs the recovery time. The recovery in patients with mild-to-moderate …

Safety and efficacy of molnupiravir in SARS‐CoV‐2‐infected patients: A real‐life experience

A De Vito, A Colpani, A Bitti, B Zauli… - Journal of Medical …, 2022 - Wiley Online Library
Since the start of the severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2)
pandemic, several treatments have been proposed to cure coronavirus disease 2019 …

[HTML][HTML] Molecular docking, binding mode analysis, molecular dynamics, and prediction of ADMET/toxicity properties of selective potential antiviral agents against …

H Rai, A Barik, YP Singh, A Suresh, L Singh, G Singh… - Molecular Diversity, 2021 - Springer
The importance of the main protease (M pro) enzyme of SARS-CoV-2 in the digestion of viral
polyproteins introduces M pro as an attractive drug target for antiviral drug design. This study …

[HTML][HTML] Tenofovir, another inexpensive, well-known and widely available old drug repurposed for SARS-COV-2 infection

I Zanella, D Zizioli, F Castelli, E Quiros-Roldan - Pharmaceuticals, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is spreading
worldwide with different clinical manifestations. Age and comorbidities may explain severity …

[HTML][HTML] Baricitinib combination therapy: a narrative review of repurposed Janus kinase inhibitor against severe SARS-CoV-2 infection

M Akbarzadeh-Khiavi, M Torabi, L Rahbarnia, A Safary - Infection, 2022 - Springer
Abstract Purpose The Coronavirus disease 2019 (COVID-19) pandemic is one of the most
devastating global problems. Regarding the lack of disease-specific treatments, repurposing …

Reduced risk of death in people with SARS-CoV-2 infection treated with remdesivir: a nested case–control study

A De Vito, M Poliseno, A Colpani, B Zauli… - Current Medical …, 2022 - Taylor & Francis
Introduction Since the start of the SARS-CoV-2 pandemic, several treatment options have
been proposed (eg steroids, heparin, antivirals and monoclonal antibodies). Remdesivir …

[HTML][HTML] De novo potent peptide nucleic acid antisense oligomer inhibitors targeting SARS-CoV-2 RNA-dependent RNA polymerase via structure-guided drug design

K Shehzadi, M Yu, J Liang - International Journal of Molecular Sciences, 2023 - mdpi.com
Global reports of novel SARS-CoV-2 variants and recurrence cases continue despite
substantial vaccination campaigns, raising severe concerns about COVID-19. While …

Lopinavir-menthol co-crystals for enhanced dissolution rate and intestinal absorption

ND Fayed, MF Arafa, EA Essa… - Journal of Drug Delivery …, 2022 - Elsevier
Lopinavir is an antiretroviral, antiparasitic agent and recently utilized in treatment of COVID-
19. Unfortunately, lopinavir exhibited poor oral bioavailability due to poor dissolution …