Immunity to malaria has been linked to the availability and function of helper CD4+ T cells,
cytotoxic CD8+ T cells and γδ T cells that can respond to both the asymptomatic liver stage …

With increasing malaria control and goals of malaria elimination, many endemic areas are
transitioning from high-to-low-to-no malaria transmission. Reductions in transmission will …

Protozoan infections are a serious global health problem,. Natural killer (NK) cells and
cytolytic T lymphocytes (CTLs) eliminate pathogen-infected cells by releasing cytolytic …

Vaccination with infectious Plasmodium falciparum (Pf) sporozoites (SPZ) administered with
antimalarial drugs (PfSPZ-CVac), confers superior sterilizing protection against infection …

Malaria parasite infection continues to inflict extensive morbidity and mortality in resource-
poor countries. The insufficiently understood parasite biology, continuously evolving drug …

Tumour− specific, immuno− based therapeutic interventions can be considered as safe and
effective approaches for cancer therapy. Exploitation of nano− vaccinology to intensify the …

The discovery of vitamin D receptor (VDR) expression in immune cells has opened up a new
area of research into immunoregulation by vitamin D, a niche that is distinct from its classical …

Nearly half of the world's population is at risk of malaria, a disease caused by the protozoan
parasite Plasmodium, which is estimated to cause more than 240,000,000 infections and kill …

Nanotechnologies are considered to be of growing importance to the vaccine field. Through
decoration of immunogens on multivalent nanoparticles, designed nanovaccines can elicit …

Despite decades of research and recent clinical trials, an efficacious long‐lasting
preventative vaccine for malaria remains elusive. This parasite infects mammals via …