The medial septum (MS), as part of the basal forebrain, supports many physiological
functions, from sensorimotor integration to cognition. With often reciprocal connections with …

Electrical brain stimulation has become an essential treatment option for more than one third
of epilepsy patients who are resistant to pharmacological therapy and are not candidates for …

Owing to its unique connectivity profile with cortical brain regions, and its suggested role in
the subcortical propagation of seizures, the anterior nucleus of the thalamus (ANT) has been …

Epilepsy is a chronic neurological disorder caused by abnormal neuronal activity that is
diagnosed visually by analyzing electroencephalography (EEG) signals. Background …

Epilepsy is not well controlled by current anti-seizure drugs (ASDs). High mobility group box
1 (HMGB1) is a DNA-binding protein in the nucleus regulating transcriptional activity and …

Neurostimulation for the treatment of epilepsy is surprisingly varied. Flexibility and
reversibility of neurostimulation allows for rapid innovation. There remains a continued need …

Cognitive impairment is the most common complication in patients with temporal lobe
epilepsy with hippocampal sclerosis. There is no effective treatment for cognitive …

Objectives To identify factors affecting the development of drug‐resistant epilepsy (DRE),
and establish a reliable nomogram to predict DRE development in post‐traumatic epilepsy …

Temporal lobe epilepsy (TLE) is a common kind of refractory epilepsy. More than 30% TLE
patients were multi-drug resistant. Some patients may even develop into status epilepticus …

Theta is one of the most prominent extracellular synchronous oscillations in the mammalian
brain. Hippocampal theta relies on an intact medial septum (MS) and has been consistently …